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Patient and healthcare providers' perspectives on participation in a postpartum pilot trial of venous thromboembolism prophylaxis: A qualitative study.
J Thromb Haemost
March 2025
Department of Medicine, University of Calgary, AB, Canada. Electronic address:
Background: There is a need to better understand barriers to recruitment and participation in randomized controlled trials (RCTs) evaluating postpartum thromboprophylaxis, as previous trials had low recruitment and were not feasible. In a qualitative interview study of the pilot PARTUM trial (a feasibility trial of low-dose aspirin versus placebo for six weeks postpartum), we explored the facilitators and barriers to trial involvement.
Methods: Patients eligible for the pilot PARTUM trial, including those who declined joining the trial, were invited to participate in a qualitative study.
AI explainability in oculomics: how it works, its role in establishing trust, and what still needs to be addressed.
Prog Retin Eye Res
March 2025
Toku Eyes Limited NZ, 110 Carlton Gore Road, Newmarket, Auckland, 1023, New Zealand; Department of Ophthalmology, University of the Sunshine Coast, Queensland, Australia. Electronic address:
Recent developments in artificial intelligence (AI) have seen a proliferation of algorithms that are now capable of predicting a range of systemic diseases from retinal images. Unlike traditional retinal disease detection AI models which are trained on well-recognised retinal biomarkers, systemic disease detection or "oculomics" models use a range of often poorly characterised retinal biomarkers to arrive at their predictions. As the retinal phenotype that oculomics models use may not be intuitive, clinicians have to rely on the developers' explanations of how these algorithms work in order to understand them.
View Article and Find Full Text PDFAir pollution and cortical myelin T1w/T2w ratio estimates in school-age children from the ABCD and NeuroSmog studies.
Dev Cogn Neurosci
February 2025
Department of Population and Public Health Sciences, Keck School of Medicine of University of Southern California, Los Angeles, CA 90063, USA; Children's Hospital Los Angeles, Los Angeles, CA 90027, USA. Electronic address:
Air pollution affects human health and may disrupt brain maturation, including axon myelination, critical for efficient neural signaling. Here, we assess the impact of prenatal and current long-term particulate matter (PM) and nitrogen dioxide (NO) exposure on cortical T1w/T2w ratios - a proxy for myelin content - in school-age children from the Adolescent Brain Cognitive Development (ABCD) Study (United States; N = 2021) and NeuroSmog study (Poland; N = 577), using Siemens scanners. Across both samples, we found that NO and PM were not significantly associated with cortical T1w/T2w except for one association of PM with lower T1w/T2w in the precuneus in NeuroSmog.
View Article and Find Full Text PDFInequities and Progress in Testicular Torsion Care Following a US News & World Report Metric: A Retrospective Cohort Study.
J Pediatr Surg
March 2025
Department of Urology, SUNY Upstate Medical University, 750 E Adams St, Syracuse, NY, USA.
Background And Objectives: Pediatric testicular torsion is a surgical emergency with known health disparities. The US News and World Report is an American media company that ranks colleges and hospitals based on annually published criteria. Hospitals that complied with the US News and World Report's (USNWR) Speed in Treating Testicular Torsion (SiTTT) metric saw improved surgical testicular salvage rates, but the metric's impact in mitigating inequities in testicular torsion is unstudied.
View Article and Find Full Text PDFImpact of age and educational qualifications on food label awareness: A study of edible oils and fats in India.
Nutrition
February 2025
CSIR-National Institute of Science Communication and Policy Research (NIScPR), New Delhi, India; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India. Electronic address:
Background: Consumer awareness of food labels plays a crucial role in promoting informed purchasing decisions and healthier dietary habits. However, the extent to which demographic factors such as age and education influence this awareness remains underexplored in the Indian context.
Objective: This study investigates the influence of age and education on consumer awareness of food labels of the edible oils and fats in India.
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