Covering 2015. Previous review: Nat. Prod. Rep., 2018, 35, 1294-1329This review covers the isolation and structure determination of triterpenoids reported during 2015 including squalene derivatives, lanostanes, holostanes, cycloartanes, cucurbitanes, dammaranes, euphanes, tirucallanes, tetranortriterpenoids, quassinoids, lupanes, oleananes, friedelanes, ursanes, hopanes, serratanes, isomalabaricanes and saponins; 320 references are cited.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1039/c9np00067d | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Advancements in Betulinic Acid-Loaded Nanoformulations for Enhanced Anti-Tumor Therapy.
Int J Nanomedicine
January 2025
Department of Pharmacy, the Affiliated Hospital, Southwest Medical University, Luzhou, People's Republic of China.
Betulinic acid (BA) is a natural compound obtained from plant extracts and is known for its diverse pharmacological effects, including anti-tumor, antibacterial, anti-inflammatory, antiviral, and anti-atherosclerotic properties. Its potential in anti-tumor therapy has garnered considerable attention, particularly for the treatment of breast, lung, and liver cancers. However, the clinical utility of BA is greatly hindered by its poor water solubility, low bioavailability, and off-target toxicity.
View Article and Find Full Text PDFA review of the traditional uses, phytochemistry, pharmacology and toxicity for the genus Geum (Rosaceae).
Fitoterapia
January 2025
School of Pharmacy, Ningxia Medical University, Yinchuan 750004, China; Key Laboratory of Protection, Development and Utilization of Medicinal Resources in Liupanshan Area, Ministry of Education, China; Key Laboratory of Ningxia Minority Medicine Modernization, Ministry of Education, Yinchuan 750004, China.. Electronic address:
The genus Geum (family Rosaceae) comprises about 70 species, of which several species have been characterized from Eurasia as notably as folk medicines for the treatment of anti-inflammatory, antiseptic, diuretics and astringent. Phytochemical analysis indicated that Geum species produce monoterpenoids, sesquiterpenes, triterpenoids, flavonoids, tannins, phenylpropanoids, and others compounds. Additionally, modern studies have found they possess diverse pharmacological activities such as antioxidant, anti-inflammatory, neuroprotective, antimicrobial, anti-diabetic, cardiovascular, and antitumor effects.
View Article and Find Full Text PDFFrom Plant to Patient: A Historical Perspective and Review of Selected Medicinal Plants in Dermatology.
JID Innov
January 2025
Department of Dermatology, Emory University School of Medicine, Atlanta, Georgia, USA.
Skin conditions are a common health concern faced by patients of all ages. For thousands of years, plants have been used to treat various skin conditions, including acne, vitiligo, and psoriasis, to name a few. Today, with increasing patient preference for natural therapies, modern medicine is now more than ever incorporating age-old knowledge of herbal remedies useful in treating skin conditions into modern-day treatments.
View Article and Find Full Text PDFRabdosia rubescens (Hemsl.) H. Hara: A potent anti-tumor herbal remedy - Botany, phytochemistry, and clinical applications and insights.
J Ethnopharmacol
December 2024
Department of Pharmacy, Fourth Affiliated Hospital of Harbin Medicine University, Harbin, 150001, Heilongjiang, China. Electronic address:
Ethnopharmacological Relevance: Traditional Chinese herbal medicine has unique advantages as anti-cancer drugs and adjuvant therapies. Rabdosia rubescens (Hemsl.) H.
View Article and Find Full Text PDFFungerps: discovery of the glucan synthase inhibitor enfumafungin and development of a new class of antifungal triterpene glycosides.
Nat Prod Rep
December 2024
Fundación MEDINA, Avda Conocimiento 34, 18016 Granada, Spain.
Covering: up to 2024Fungal pathogens are a major threat to public health, with emerging resistance to all three classes of antifungals that are currently available and increased incidence of invasive fungal infections among hospitalized patients. Ibrexafungerp is a semi-synthetic analog of enfumafungin and the first antifungal agent approved in more than 20 years since the launch of caspofungin, the first of echinocandins. This new drug approval was made possible after a long arduous journey lasting 25 years by dedicated and talented medicinal chemists from two companies that undertook tedious atom-by-atom chemical modification of the natural product enfumafungin, a glycosylated fernane-type triterpenoid isolated from the fungus .
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!