AI Article Synopsis
- * These new trifluoromethoxide salts have demonstrated long-term stability, both as solids and in solution, which is beneficial compared to existing reagents.
- * The paper details the preparation of various NROCF salts, evaluates their stability over time, and discusses their applications in substitution reactions.
Article Abstract
The reaction of nucleophilic tertiary amines with trifluoromethyl and pentafluoroethyl methyl ethers provides quaternary ammonium trifluoromethoxide (NROCF) and pentafluoroethoxide (NROCFCF) salts, respectively, in good yields. The new trifluoromethoxide salts disclosed herein are uniquely stable for extended periods of time in both the solid state and in solution, which complements contemporary reagents. Here we describe the preparation of a range of NROCF salts, their long-term stability, and utility in substitution reactions.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1021/acs.orglett.0c00099 | DOI Listing |
Publication Analysis
Top Keywords
quaternary ammonium
8
ammonium trifluoromethoxide
8
trifluoromethoxide salts
8
salts
4
salts stable
4
stable sources
4
sources nucleophilic
4
nucleophilic ocf
4
ocf reaction
4
reaction nucleophilic
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!