Objective: To analyze the knowledge of women who are being treated in Psychosocial Care Centers for Alcohol and Drugs about the harm caused by alcohol consumption during pregnancy, especially regarding fetal malformation.
Method: Qualitative, descriptive and exploratory study using the Life Narrative approach. Data was collected between February and May 2016, in the city of Rio de Janeiro, with an open interview with the guiding question: "Tell me about your life in relation to alcohol consumption during pregnancy and the guidance received in prenatal care".
Results: The narratives revealed lack of information and fear of malformation (physical) and fetal death due to alcohol consumption during pregnancy.
Discussion: Malformation or fetal death may trigger a transitional process in women.
Final Considerations: Women have incipient knowledge about the effects of alcohol on the fetus. They consider that alcohol can only cause physical defects in the children.
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http://dx.doi.org/10.1590/0034-7167-2018-0233 | DOI Listing |
J Racial Ethn Health Disparities
January 2025
Epidemiology and Health Economics Research (EHER), Universidad Científica del Sur, Lima, Peru.
Background: The Afro-Peruvian population is one of the ethnic minorities most affected by cultural, socioeconomic, and health barriers; however, there is little evidence on health inequalities in this ethnic group. Therefore, We aimed to determine health inequalities among the Peruvian Afro-descendant population in comparison with non-Afro-descendants.
Methods: A cross-sectional study was conducted using data from the Demographic and Family Health Survey 2022.
Alzheimers Dement
December 2024
School of Pharmacy, Chapman University, Irvine, CA, USA.
Background: Chronic heavy alcohol drinking may be a modifiable risk factor for Alzheimer's disease (AD), but studies in rodent AD models more closely mimic chronic moderate alcohol drinking in humans and largely focus on the brain. The role of the liver, which is significantly impacted by chronic heavy alcohol intake, in driving brain changes in alcohol-dependent AD remains unexplored. Our study using intragastric-ethanol feeding, which mimics chronic heavy alcohol intake in humans, in C57BL/6J mice showed significant AD-relevant changes in the brain and liver.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
University of Louisville, Lousiville, KY, USA.
Background: Chronic, excessive alcohol consumption causes neurodegeneration and is associated with an increased risk for Alzheimer's disease (AD) and other dementias. Moreover, there has been a consistent rise in alcohol consumption in older adults in the past few decades. However, there is minimal research showing how alcohol consumption affects AD neuropathogenesis and biological mechanisms remain unclear.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Biobank for Aging Studies of the University of São Paulo, São Paulo, Brazil.
Background: Previous studies suggest an association between Alzheimer's disease and carotid artery atherosclerosis. However, the association between atherosclerotic carotid plaque composition and Alzheimer's disease pathology (neuritic plaques and neurofibrillary tangles) has not been explored yet.
Method: Carotid arteries were dissected and the segments with the largest obstruction in the carotid bifurcation, and the common and internal carotid arteries were obtained.
Alzheimers Dement
December 2024
Biobank for Aging Studies of the University of São Paulo, São Paulo, Brazil.
Background: Transactive DNA-binding protein 43 (TDP-43) proteinopathy is associated with neurodegeneration, including LATE and linked to cognitive deterioration. While some research suggests a higher prevalence of TDP-43 in women, no differences have been identified among racial groups. Nonetheless, the influence of gender on cognition within the context of TDP-43 remains uncertain.
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