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Multiple system atrophy: Diagnostic challenges and a proposed diagnostic algorithm.
Clin Park Relat Disord
September 2024
The Parkinson and Movement Disorder Institute, 9940 Talbert Avenue, Fountain Valley, CA 92708, USA.
Article Synopsis
- Multiple system atrophy (MSA) is a complex disorder characterized by autonomic dysfunction, parkinsonism, and/or cerebellar ataxia, marked by the presence of alpha-synuclein glial cytoplasmic inclusions.
- MSA shares similarities with Parkinson's disease and Lewy body dementia, as they all fall under the category of "synucleinopathies," with pathological synuclein protein detectable in skin biopsies of affected patients.
- While various diagnostic tools like brain MRI and cardiac MIBG scans are useful for identifying MSA, there's a need for clarity on when to use them, leading to the proposal of a diagnostic algorithm that complements existing MDS criteria without replacing them.
Frog sign and AV nodal reentrant tachycardia: A case report.
Int J Crit Illn Inj Sci
September 2021
Department of Cardiology, St. Luke's University Hospital, Fountain Hill, Easton, PA, USA.
Supraventricular tachycardia is one the most frequent cardiac arrhythmias seen in patients, with AVNRT being the most common subtype. Two subgroups of AVNRT have been reported, that of typical and atypical. "Frog Sign," long considered a classic physical exam sign, albeit rare, is associated with typical AVNRT.
View Article and Find Full Text PDFMen's and women's knowledge of danger signs relevant to postnatal and neonatal care-seeking: A cross sectional study from Bungoma County, Kenya.
PLoS One
October 2021
Directorate of Research and Innovation, Mount Kenya University, Thika, Kenya.
Background: Neonatal and maternal mortality rates remain high in Kenya. Knowledge of neonatal danger signs may reduce delay in deciding to seek care. Evidence is emerging on the influential role of male partners in improving maternal and newborn health.
View Article and Find Full Text PDFUnusual clinical scenarios in Urology and Andrology.
Arch Ital Urol Androl
March 2021
Division of Urology, University Hospital "Ospedali Riuniti", School of Medicine, Department of Clinical, Special and Dental Sciences, Marche Polytechnic University, Ancona.
This collection includes some unusual cases and how they were diagnosed and treated. Case 1: A case of a patient with primary hyperthyroidism presenting with a submucosal ureteral stone after endoscopic lithotripsy was described. After multiple endoscopic treatment, the stone was successfully removed by open ureterolithotomy recovering ureteral patency and normal renal function.
View Article and Find Full Text PDF"Fountain Sign," a Basic Finding toward the Diagnosis of Partially Thrombosed Giant Aneurysm: Describing a Challenging Case and Literature Review.
Asian J Neurosurg
December 2020
Department of Neurosurgery, Rasoul Akram Hospital, Iran University of Medical Sciences, Tehran, Iran.
Although the occurrence of cerebral aneurysms in pediatric age group describes as rare, giant ones are more commonly be found than in adults. Insufficient epidemiological information, their association with other medical comorbidities, diagnostic pitfalls, complex surgical anatomy, and issues should be considered during surgery to make them difficult to diagnose and manage. We report a 6-year-old boy with presenting complaint of acute-onset headache without any other symptoms and a small area of intracerebral hemorrhage detected on initial computed tomography (CT) scan.
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