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Towards a novel framework for identifying commonalities and differences in older people's end-of-life trajectories: aims and interdisciplinary mixed-methods approach of the ERC-funded TRAJECT project.
Palliat Care Soc Pract
December 2024
Vrije Universiteit Brussel (VUB) & Ghent University, End-of-Life Care Research Group, Brussels, Belgium.
Background: Older people who die from serious chronic disease typically experience long periods (months or years) of illness and complex fluctuations in their physical health and in their social, psychological and existential well-being. Our understanding of these end-of-life trajectories is very limited, focuses predominantly on physical function and clinical predictors and neglects inter-individual differences. A better understanding of end-of-life trajectories, including what is shared among people and what is individually specific, is needed for an optimal provision of palliative care and health services planning.
View Article and Find Full Text PDFHeritable Burden of Community Sudden Death by Autopsy and Molecular Phenotyping for Precision Genotype Correlation.
JACC Clin Electrophysiol
December 2024
Office of the Chief Medical Examiner, City and County of San Francisco, San Francisco, California, USA.
Background: Sudden cardiac death (SCD) genetic studies neglect the majority occurring in older decedents with cardiovascular pathology.
Objectives: This study sought to determine the burden of genetic disease in unselected adult sudden deaths by precision genotype-postmortem phenotype correlation.
Methods: The authors used autopsy, histology, and toxicology to adjudicate cause and identify high-suspicion phenotypes (eg, hypertrophic cardiomyopathy) among presumed SCDs aged 18 to 90 years referred to the county medical examiner from February 2011 to January 2018.
Global burden of myocarditis from 1990 to 2021: findings from the Global Burden of Disease Study 2021.
BMC Cardiovasc Disord
December 2024
Department of Cardiology, The Second Hospital of Shanxi Medical University, 382 Wuyi Road, Taiyuan, Shanxi, 030001, China.
Background: Myocarditis is a major public health, social, and economic issue. Currently, few studies have provided comprehensive analyses of the global burden of myocarditis based on GBD (Global Burden Disease) 2021. We therefore analyzed long-term trends in the global burden of myocarditis from 1990 to 2021, described risk factors, examined the impact of COVID-19 (coronavirus infection disease 2019), and predicted future trends to inform health policy development and healthcare resource allocation.
View Article and Find Full Text PDFIntrinsic capacity and its association with predictors among Chinese empty nest older adults in communities: a latent class analysis.
BMC Geriatr
December 2024
Department of Nursing, Daqing Campus, Harbin Medical University, 39 Xinyang Road, Daqing, 163319, China.
Objectives: This study aimed to examine Intrinsic Capacity (IC) subgroups and the association of IC subgroups with IC predictors in Chinese urban empty nesters.
Methods: A convenient sample of 385 older adults aged 60 and above in Community Health Service Center was recruited from Hei Longjiang Province, China, between June 2023 and December 2023. Latent class Analysis (LCA) was conducted to explore IC subgroups using the sensory, cognition, locomotion, psychological, and vitality domains of IC as input variables.
Developing a theory of change to guide the design and implementation of a caregiver-centric support service.
BMC Health Serv Res
December 2024
Nursing Implementation, Translation and Research Office (NITRO), Tan Tock Seng Hospital, Nursing Service, Annex 1, Level 1, 11 Jln Tan Tock Seng, Singapore, 308443, Singapore.
Background: Set against the backdrop of a rapidly ageing population and growing emphasis on the importance of ageing-in-place, family members often assume the role of a caregiver. Navigating through a complex healthcare system while simultaneously juggling the daily care needs of their care-recipients, caregivers often become worn out by the intense caregiver stress and burden, neglecting their own well-being. This translates to adverse health and economic outcomes such as prolonged hospital stays and increased nursing home placement of care-recipients.
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