Relationship between CNR and visibility of anatomical structures of cone-beam computed tomography images under different exposure parameters.

Objectives: The purpose of this study was to investigate the image quality of cone beam CT (CBCT) under different exposure parameters and the relationship between contrast-to-noise and visibility of eight anatomical structures.

Methods: CBCT images for the evaluation of subjective image quality were acquired on an anthropopathic phantom containing a human skeleton embedded in soft tissue equivalent materials using 25 exposure protocols. Visibility of eight anatomical structures was evaluated by five independent observers. Using the SEDENTEXCT IQ Image Quality phantom, the contrast-to-noise ratio (CNR) was calculated by ImageJ software.

Results: A reduction on the visibility of anatomical structures was seen under lower exposure parameters. However, for 84% of the protocols, visibility of anatomical structures remained acceptable even under some lower parameter settings. As CNR increased, the visibility of anatomical structures also increased correspondingly. A change point could be found in the CNR interval 29.42-36.51 after which the visibility of anatomical structures no longer increases with the increase of CNR.

Conclusions: Although CNR decrease under a lower exposure parameter, the image quality often remained acceptable at exposure levels below the manufacture's recommended settings. It is possible to standardize subjective image quality by physical factors. Currently, it is not possible to predetermine a change point CNR value due to different CBCT machine and variation of diagnostic tasks.