Background: Foot and mouth disease (FMD), which causes myocarditis, results in 50% sudden death in the suckling calves. Occurrence of arrhythmias associated with FMD induced myocarditis in calves is not reported . The present work documents the arrhythmias associated with FMD in calf and their treatment using appropriate antiarrhythmic drugs.
Case Description: A three -month-old male Holstein Friesian crossbred calf naturally suffering from FMD was selected for the present study.
Findings/treatment And Outcome: Cardiac auscultation revealed grade 4 systolic murmurs and electrocardiography (ECG) showed sustained polymorphic ventricular premature complexes (PVPCs) with tachycardia on bipolar base apex lead. Apart from standard treatment, lidocaine 2% was administered at dose of 0.6 mg/kg intravenously over 15 min once a day and sinus rhythm was restored by 76 h post-treatment. Review of ECG and haematobiochemical examination revealed normal findings on 7th day of treatment.
Conclusion: The study demonstrates the presence of sustained PVPCs with tachycardia due to FMD induced myocarditis and the successful use of lidocaine in restoring the sinus rhythm and recovery of the calf.
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Vet Q
December 2025
College of Veterinary Medicine, Northeast Agricultural University, Harbin, China.
Foot-and-Mouth Disease is a highly contagious transboundary animal disease. FMD has caused a significant economic impact globally due to direct losses and trade restrictions on animals and animal products. This study utilized multi-distance spatial cluster analysis, kernel density analysis, directional distribution analysis to investigate the spatial distribution patterns of historical FMD epidemics.
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Department of Micrology, College of Medicine, Taif University, Taif, 21944, Egypt.
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Division of Microbiology, Faculty of Veterinary Medicine, Universitas Airlangga, Surabaya, Indonesia.
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Girijananda Chowdhury Institute of Pharmaceutical Science (Affiliated to Assam Science and Technology University), Guwahati, 781017, Assam, India; Phytochemical Research Laboratory, School of Pharmaceutical Sciences, Girijananda Chowdhury University, Guwahati, 781017, Assam, India. Electronic address:
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January 2025
Indian Council of Agricultural Research (ICAR)-Indian Veterinary Research Institute (IVRI), Hebbal, Bengaluru 560024, India. Electronic address:
As pregnancy can adversely affect the immune response of vaccination against foot and mouth disease virus (FMDV) due to physiological immunosuppressive milieu, we tested the effect of FMDV vaccination during mid-gestation on the antibody response. Pregnant and non-pregnant cows of crossbred and indigenous breed (n = 28/group) were vaccinated with inactivated FMD vaccine covering O, A, and Asia1 serotypes and the sera were harvested at weekly interval till day 42 post-vaccination. Virus neutralization test (VNT) was done and the analysis of log VN antibody titer by mixed model ANOVA indicated that pregnancy did not significantly affect the log VN titer for FMDV serotype O and Asia1.
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