Treatment of relapsed refractory T-PLL with venetoclax monotherapy results in only transient and minor clinical responses. In vitro analyses pre- and postvenetoclax indicate dual dependence on BCL2 and MCL1; combined BCL2 and MCL1 inhibition are synergistic.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7013268 | PMC |
| http://dx.doi.org/10.1182/bloodadvances.2019000917 | DOI Listing |
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