Purpose: To create automated tools within the treatment planning system (TPS) that eliminate the common error pathway of providing incorrect shift instructions to therapists.
Materials/methods: Two scripts were created within the TPS using the Eclipse API (Varian Medical Systems, Palo Alto, CA). One script detects whether or not the user origin has been placed correctly at the intersection of the simulation markers while the other calculates a shift instruction sheet that can be printed for treatment.
Results: Analysis of our RO-ILS database identified eight errors caused by improper setting of the user origin in the treatment planning system. The user origin script flagged all of the treatment plans for markers inconsistent with user origin. Automated calculation of shifts eliminated the error pathway of miscalculating or transcribing shift values.
Conclusion: Automation can eliminate the common error pathway of providing the wrong shifts to therapists. The scripts have been made available as open-source software for implementation at other radiotherapy clinics.
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http://dx.doi.org/10.1002/acm2.12830 | DOI Listing |
Sci Adv
January 2025
Department of Biostatistics and Health Data Science, School of Medicine, Indiana University, Indianapolis, IN 46202, USA.
Alzheimer's disease (AD) is the leading dementia among the elderly with complex origins. Despite extensive investigation into the AD-associated protein-coding genes, the involvement of noncoding RNAs (ncRNAs) and posttranscriptional modification (PTM) in AD pathogenesis remains unclear. Here, we comprehensively characterized the landscape of ncRNAs and PTM events in 1460 samples across six brain regions sourced from the Mount Sinai/JJ Peters VA Medical Center Brain Bank Study and Mayo cohorts, encompassing 33,321 long ncRNAs, 92,897 enhancer RNAs, 53,763 alternative polyadenylation events, and 900,221 A-to-I RNA editing events.
View Article and Find Full Text PDFEnviron Monit Assess
January 2025
Waste and Resource Management, Rostock University, Justus-Von-Liebig-Weg 6, 18059, Rostock, Germany.
We conducted surveys of Mediterranean beaches in Egypt, Morocco, and Tunisia including 37 macro-litter (> 25 mm) and 41 meso-litter (5-25 mm) assessments. Our study identified key litter items and assessed pollution sources on urban, semi-urban, tourist, and semi-rural beaches. Macro-litter concentration averaged 5032 ± 4919 pieces per 100 m or 1.
View Article and Find Full Text PDFBehav Brain Sci
January 2025
Department of Applied Psychology and Human Development, University of Toronto, Toronto, ON,
Sijilmassi et al. argue that myths serve to gain coalitional support by detailing shared histories of ancestry and cooperation. They overlook the emotional influences of stories, which include myths of human origin.
View Article and Find Full Text PDFImeta
December 2024
Children's Hospital Zhejiang University School of Medicine, National Clinical Research Center for Child Health Hangzhou China.
First introduced in 2021, MetOrigin has quickly established itself as a powerful web server to distinguish microbial metabolites and identify the bacteria responsible for specific metabolic processes. Building on the growing understanding of the interplay between the microbiome and metabolome, and in response to user feedback, MetOrigin has undergone a significant upgrade to version 2.0.
View Article and Find Full Text PDFMethodsX
June 2025
Social Anthropology Department, Faculty of Social Science and Political Science, Universitas Sumatera Utara, Indonesia.
This paper presents a novel approach to addressing the challenge of stunting in impoverished rural areas of North Sumatra, Indonesia, through the use of illustrated educational modules in the local Nias language. Stunting, a significant health issue affecting young children's physical and cognitive development, is prevalent in these communities. Traditional educational methods using the national language have proven ineffective due to cultural and linguistic barriers.
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