Anorexia nervosa is a psychiatric eating disorder related to malnutrition and consequent altered metabolism. A 48-year-old female with a history of anorexia in the last 2 years referred to our hospital with spinal pain. She underwent spinal X-ray and magnetic resonance imaging (MRI) showing multiple vertebral collapses in dorsal and lumbar spine with inversion of normal bone marrow and soft tissue signal in T1-weighted and STIR images. We describe this case of spinal 'flip-flop' phenomenon, underlining how what seems a technical failure is actually a specific imaging pattern related to the clinical context.
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http://dx.doi.org/10.1111/1754-9485.12985 | DOI Listing |
J Pharmacol Exp Ther
December 2023
Department of Pharmaceutics (B.M.C., C.D.P., C.A.F.), Department of Pharmacology (L.D.C., G.L.W., C.A.F.), Department of Neuroscience (K.F.K., G.L.W., C.A.F.), and Department of Dermatology (G.L.W.), University of Minnesota, Minneapolis, Minnesota
Agmatine, an endogenous polyamine, has been shown to reduce chronic pain behaviors in animal models and in patients. This reduction is due to inhibition of the GluN2B subunit of the N-methyl-D-aspartate receptor (NMDAR) in the central nervous system (CNS). The mechanism of action requires central activity, but the extent to which agmatine crosses biologic barriers such as the blood-brain barrier (BBB) and intestinal epithelium is incompletely understood.
View Article and Find Full Text PDFJ Radiol Case Rep
June 2021
. Department of Clinical Radiology, Royal Stoke University Hospital; Stoke-on-Trent, United Kingdom.
A 66-year-old cachectic female with underlying anorexia nervosa and lower limb weakness was referred for a spinal Magnetic Resonance Imaging. Imaging appearances were initially thought to represent underlying systemic pathology involving bone marrow or inadvertent wrong selection of imaging sequences. It was, however, established that unique imaging appearances are secondary to 'Flip-Flop' phenomenon owing to underlying nutritional status of the patient.
View Article and Find Full Text PDFJ Med Imaging Radiat Oncol
August 2020
Neuroradiology Unit, San Bortolo Hospital, Vicenza, Italy.
Anorexia nervosa is a psychiatric eating disorder related to malnutrition and consequent altered metabolism. A 48-year-old female with a history of anorexia in the last 2 years referred to our hospital with spinal pain. She underwent spinal X-ray and magnetic resonance imaging (MRI) showing multiple vertebral collapses in dorsal and lumbar spine with inversion of normal bone marrow and soft tissue signal in T1-weighted and STIR images.
View Article and Find Full Text PDFJ Spinal Cord Med
September 2021
Department of Neurology, Xuanwu Hospital, Capital Medical University, Beijing, People's Republic of China.
Syphilitic meningomyelitis is a rare manifestation of neurosyphilis, not well described in the literature. We reported a rare case of a 29-year-old female with syphilitic meningomyelitis. Her clinical manifestations and imaging findings were discussed with the related literatures reviewed.
View Article and Find Full Text PDFWorld J Clin Cases
June 2019
Department of Neurology, Beijing Chaoyang Hospital, Capital Medical University, Beijing 100020, China.
Background: Syphilitic myelitis caused by is an extremely rare disease. However, symptomatic neurosyphilis, especially syphilitic myelitis, and its clinical features have been infrequently reported. Only a few cases of syphilitic myelitis have been documented.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!