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Susac Syndrome with Classical Triad: A Case Report and Literature Review.
Ann Afr Med
March 2025
Department of Ophthalmology, College of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.
Susac syndrome is a rare microangiopathy affecting the brain, retina, and cochlea. Individuals affected typically present with a classical clinical triad of branch retinal artery occlusion (BRAO), encephalopathy or white matter lesions, and sensorineural hearing loss. Herein, we report an exceedingly rare case of a middle-aged female patient with multiple presentations related to her visual field complaints.
View Article and Find Full Text PDFSuccessful Natalizumab Treatment of Two Female Individuals With Susac Syndrome.
Eur J Neurol
March 2025
Department of Neurology, University Hospital Marburg, Marburg, Germany.
Background: Susac syndrome is a rare autoimmune endotheliopathy that affects the central nervous system, retina, and inner ear, characterized by encephalopathy, branch retinal artery occlusions, and sensorineural hearing loss. Due to the heterogeneity of its presentation, early diagnosis, and treatment remain challenging.
Objective/methods: To evaluate the clinical outcomes and radiological responses in two patients with Susac syndrome treated with natalizumab in an off-label therapeutic approach, clinical assessments and serial magnetic resonance imaging (MRI) were performed over a follow-up period of up to 22 months to monitor disease progression and treatment response.
Vision Loss in an Infantryman With Complex Hearing Loss: Case Report and Review of Susac Syndrome.
Mil Med
January 2025
Department of Ophthalmology, Naval Medical Center San Diego, 34800 Bob Wilson Dr, Suite 202, San Diego, CA 92134, USA.
Susac syndrome can resemble various disorders resulting in a delayed or missed diagnosis and subsequent delays in treatment. Here, we present how successful consideration of patient history, symptoms, and ancillary testing led to prompt diagnosis and treatment of Susac syndrome by ophthalmologists. A 27-year-old active duty infantryman presented with sudden vision loss in the right eye during strenuous exercise after experiencing similar symptoms in the left eye 5 months earlier.
View Article and Find Full Text PDFSpinal cord involvement in Susac Syndrome: a unique paediatric case.
Rheumatology (Oxford)
January 2025
Department of Pédiatrie Générale, Assistance Publique et Hôpitaux de Marseille (AP-HM), Marseille, France.
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