AI Article Synopsis
- * A study analyzed the genetic differences between two closely related species, focusing on specific nucleotide substitutions and inversion frequencies in 289 larvae from the Moscow region.
- * Results showed significant genomic divergence, especially on the inversion-rich X chromosome, indicating that inversions contribute to the limited reproductive isolation between these two species.
Article Abstract
Chromosomal inversions are important drivers of genome evolution. The Eurasian malaria vector has five polymorphic inversions. A cryptic species, , has been discriminated from based on five fixed nucleotide substitutions in the internal transcribed spacer 2 (ITS2) of ribosomal DNA. However, the inversion polymorphism in and the genome divergence between these species remain unexplored. In this study, we sequenced the ITS2 region and analyzed the inversion frequencies of 289 larvae specimens collected from three locations in the Moscow region. Five individual genomes for each of the two species were sequenced. We determined that and differ from each other by the frequency of polymorphic inversions. Inversion X1 was fixed in but polymorphic in populations. The genome sequence comparison demonstrated genome-wide divergence between the species, especially pronounced on the inversion-rich X chromosome (mean Fst = 0.331). The frequency of polymorphic autosomal inversions was higher in than in We conclude that the X chromosome inversions play an important role in the genomic differentiation between the species. Our study determined that and are closely related species with incomplete reproductive isolation.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7074279 | PMC |
| http://dx.doi.org/10.3390/genes11020165 | DOI Listing |
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