Glenoid bone loss is frequently encountered in arthritic conditions. The Walch classification is commonly used to categorize glenoid bone loss into several different types. Preoperative CT can assist in identifying the type and extent of bone loss for development of the appropriate treatment plan. Restoration of glenoid alignment and soft-tissue balancing is essential in shoulder arthroplasty, which can be achieved through a variety of techniques including high side reaming, augmented components, and bone grafting. Reverse total shoulder arthroplasty, another viable option to address severe bone deficiency, may be performed in conjugation with bone grafting or augmented components. Extensive bone loss may also be addressed in a staged procedure or avoided with isolated humeral head replacement. Humeral bone loss also remains a challenge in patients undergoing shoulder arthroplasty, which may be addressed with an allograft-prosthesis composite or an isolated metal prosthesis. Further investigation into the use of different biomaterials, ceramics, endosteal fixation, and modular components is needed. There are promising results with computer-assisted component implantation.
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Int J Rheum Dis
January 2025
Department of Orthopaedics, Xiangya Hospital, Central South University, Changsha, Hunan, China.
Objective: Serum uric acid (SUA) may play positive roles in diseases associated with oxidative stress, such as osteoporosis (OP). Nevertheless, the specific impact of SUA levels on both bone mineral density (BMD) and the risk of OP remains uncertain. Considering such information crucial for clinicians when making decisions about urate-lowering therapy (ULT), we sought to fill this gap by conducting dose-response meta-analyses.
View Article and Find Full Text PDFAdv Mater
January 2025
Department of Orthopaedics Shanghai Key Laboratory for Prevention and Treatment of Bone and Joint Diseases, Shanghai Institute of Traumatology and Orthopaedics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, 197 Ruijin 2nd Road, Shanghai, 200025, P. R. China.
High transductive loss at tissue injury sites impedes repair. The high dissipation characteristics in the electromechanical conversion of piezoelectric biomaterials pose a challenge. Therefore, supramolecular engineering and microfluidic technology is utilized to introduce slide-ring polyrotaxane and conductive polypyrrole to construct stress-electric coupling hydrogel microspheres.
View Article and Find Full Text PDFWorld J Orthop
December 2024
Department of Orthopaedics, Brazilian Institute of Regenerative Medicine, Indaiatuba 13334-170, São Paulo, Brazil.
The gut microbiome, a complex ecosystem of microorganisms in the digestive tract, has emerged as a critical factor in human health, influencing metabolic, immune, and neurological functions. This review explores the connection between the gut microbiome and orthopedic health, examining how gut microbes impact bone density, joint integrity, and skeletal health. It highlights mechanisms linking gut dysbiosis to inflammation in conditions such as rheumatoid arthritis and osteoarthritis, suggesting microbiome modulation as a potential therapeutic strategy.
View Article and Find Full Text PDFImaging Sci Dent
December 2024
Department of Oral and Maxillofacial Radiology, Faculty of Dentistry, Assiut University, Assiut, Egypt.
Purpose: This study was performed to introduce, evaluate, and compare various novel assessment protocols designed for straightforward, reliable, and reproducible measurement of alveolar bone levels. These protocols are intended for standardized periodontal assessment and follow-up, utilizing cone-beam computed tomography (CBCT) images and manipulation of Digital Imaging and Communications in Medicine (DICOM) viewer software.
Materials And Methods: Two experienced oral and maxillofacial radiologists developed 5 distinct radiographic measurement protocols.
Front Endocrinol (Lausanne)
January 2025
Department of Pharmacy, New Taipei City Hospital, New Taipei City, Taiwan.
Background: The increasing prevalence of glucocorticoid-induced osteoporosis (GIOP) due to long-term glucocorticoid therapy underscores the need for effective treatment options. Denosumab and bisphosphonates, both key in managing GIOP, require further comparative evaluation to determine their relative efficacy and safety profiles.
Methods: We conducted a systematic review and meta-analysis, adhering to PRISMA guidelines.
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