Objectives: To describe the radiographic features of odontogenic keratocysts (OKCs) and ameloblastomas and to compare the radiographic findings between these 2 lesions.
Methods: Radiographs of OKCs and ameloblastomas were retrospectively reviewed. Location, border, shape, association with impacted tooth, tooth displacement, root resorption, and bone expansion were evaluated. Chi-squared or Fisher's exact tests were used for statistical analysis. A p value < 0.05 was considered to indicate statistical significance.
Results: One hundred OKCs and 101 ameloblastomas were reviewed. The ratios of maxilla to mandible were 1:1.4 and 1:9.1 in OKCs and ameloblastomas, respectively. All evaluated features significantly differed between OKCs and ameloblastomas (p ≤ 0.001). Most OKCs showed smooth border (60%) and unilocular shape (82%), while most ameloblastomas showed scalloped border (77.2%) and multilocular shape (68.3%). Association with impacted tooth was found in 47% of OKCs and 18.8% of ameloblastomas. Adjacent tooth displacement was found in 33.7% of OKCs and 55.8% of ameloblastomas. Root resorption was more common in ameloblastomas (66.7%) than in OKCs (7%). Bone expansion was also more common in ameloblastomas (96.3%) than in OKCs (63.6%).
Conclusion: A unilocular radiolucent lesion with smooth border, no adjacent tooth displacement, no root resorption and causing mild or no bone expansion is suggestive of an OKC rather than an ameloblastoma.
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http://dx.doi.org/10.1007/s11282-020-00425-2 | DOI Listing |
Appl Immunohistochem Mol Morphol
November 2024
Department of Basic Sciences, College of Dentistry, Princess Nourah bint Abdulrahman University, 84428, Riyadh 11671, Saudi Arabia.
Odontogenic cysts and tumors exhibit a broad spectrum of biological characteristics. Despite recent advances in understanding the complex nature of these lesions, relatively less is known about the molecular markers involved in key pathogenic steps, such as proliferation and differentiation. This study aimed to elucidate the expression patterns of p63 and Ki-67 in odontogenic lesions, which may influence the management strategies.
View Article and Find Full Text PDFEur J Dent
November 2024
Department of Oral Surgery and Oral Medicine, Faculty of Dentistry, Srinakharinwirot University, Bangkok, Thailand.
Objectives: Histone modification in odontogenic lesions is mostly unexplored. Trimethylation of histone H3 at lysine residue 9 (H3K9Me3) has been studied in various pathologic conditions and showed biological significance promising for future therapeutic application. This study aimed to investigate the level and clinical relevance of the H3K9Me3 histone modification in odontogenic cysts and tumors.
View Article and Find Full Text PDFInt J Med Inform
January 2025
Department of Oral Biology and Diagnostic Sciences, Faculty of Dentistry, Chiang Mai University, Suthep Road, Suthep Sub-district, Mueang Chiang Mai District, Chiang Mai 50200, Thailand. Electronic address:
Background: Radiolucent jaw lesions like ameloblastoma (AM), dentigerous cyst (DC), odontogenic keratocyst (OKC), and radicular cyst (RC) often share similar characteristics, making diagnosis challenging. In 2021, CrossViT, a novel deep learning approach using multi-scale vision transformers (ViT) with cross-attention, emerged for accurate image classification. Additionally, we introduced Extended Cropping and Padding (ECAP), a method to expand training data by iteratively cropping smaller images while preserving context.
View Article and Find Full Text PDFThe aim of this study was to evaluate the histopathologic diagnoses and radiographic characteristics of lesions associated with impacted teeth. In this retrospective study, 2624 biopsy reports were assessed. If the report was a record of a pericoronal lesion, the age and sex of the patient and the location, microscopic diagnosis, radiographic features, and size of the lesion were recorded.
View Article and Find Full Text PDFCureus
September 2024
Department of Oral Pathology, Manav Rachna Dental College, Faridabad, IND.
The term "unicystic ameloblastoma" describes cystic lesions that exhibit radiographic, clinical, or gross characteristics of a jaw cyst. However, histologic examination reveals a typical ameloblastomatous epithelium lining the cyst cavity, with or without luminal and/or mural tumor proliferation. Unicystic ameloblastoma is a less prevalent kind of ameloblastoma.
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