A BODIPY-based fluorescent sensor for the detection of Pt2+ and Pt drugs.

Chem Commun (Camb)

Department of Chemistry, State Key Laboratory of Environmental and Biological Analysis, Hong Kong Baptist University, Kowloon Tong, Hong Kong SAR, P. R. China.

Published: March 2020

A BODIPY-based fluorescent sensor PS with an NO4S2 podand ligand was studied for the selective detection of Pt2+ over 21 cations as well as selected platinum drugs in aqueous medium. The platinum sensor PS shows 28-fold, 22-fold and 14-fold fluorescence turn-on enhancements to Pt2+, cisplatin and nedaplatin, and was thereby employed to detect platinum drugs in A-549 human lung cancer cells.

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Source
http://dx.doi.org/10.1039/d0cc00027bDOI Listing

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