Relationship between environmental Fungi and changes in lung function indices of new referral allergic patients in Ahvaz city under normal and dust conditions.

Background: Aim of this study was to determine whether any specific fungal spores could be responsible for changes observed in lung function indices.

Materials And Methods: 1042 new allergic patients were selected from July 2017 to May 2018 in Ahvaz City, Iran. Fungal samples were collected in normal and dusty condition within 5 and 2 min, respectively. Sampling was repeated once every 6 days and also in the dusty days.

Results: Average numbers of fungi colony were 639.86 and 836.44 CFU m under normal and dusty conditions, respectively. Most common fungi in Ahwaz City air were , , , and Highest fungal mean concentrations, 392 and 480 CFU m, were related to under normal and dust conditions, respectively. Average total numbers of colony fungal were 614, 483, 1082, 424 CFU m and 856, 701, 1418, 418 CFU m during the spring, summer, autumn, and winter under normal and dusty conditions, respectively. Patients were evaluated by measured lung function parameters of FEV (L), FEV (%pred), FVC (L), FVC (%pred), and FEV/FVC ratio with mean values of 1.85, 58.32, 2.63, 68.18, and 69.43, respectively.

Conclusion: Increases in mean total spores of fungi in spring were accompanied by decreases in FEV/FVC ratio. Enhanced spores of in spring led to reduced FEV/FVC ratio. Increase the spores of in summer decreased by FEF. The augmented spores of in summer were associated with declined FEV and FEV/FVC ratio. Enhanced fungal spores of in spring resulted in lowered FEV, FEV/FVC ratio, and FEF.