AI Article Synopsis
Article Abstract
Control of gastrointestinal nematodes has been based on anthelmintics. However, this strategy is unsustainable owing to anthelmintic resistance. Parasitic nematodes have biologic and genetic features that favor the development of drug resistance, making the emergence of resistant nematodes inevitable. The rate of resistance development is affected controllable factors. There is a need to change the paradigm of how gastrointestinal nematodes are controlled to decrease the rate at which resistance develops. This article reviews the biology and prevalence of anthelmintic resistance, and provides recommendations for diagnosing resistance and for strategies that should be implemented to reduce the development of resistance.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.cvfa.2019.12.001 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
The Anthelmintic Activity of Lam. Against Gastrointestinal Nematodes of Sheep: Rosmarinic Acid Quantification and In Silico Tubulin-Binding Studies.
Pathogens
January 2025
Department of Pharmacognosy, Faculty of Pharmacy, Gazi University, Ankara 06330, Turkey.
Gastrointestinal nematodes (GINs) inflict significant economic losses on sheep and goat farming globally due to reduced productivity and the development of anthelmintic resistance. Sustainable control strategies are urgently needed including the exploration of medicinal plants as safer alternatives to chemical anthelmintics. This genus of plants is used for anti-inflammatory, antioxidant, and antimicrobial activities.
View Article and Find Full Text PDFKnowledge, attitudes and practices of Australian dairy goat farmers towards the control of gastrointestinal parasites.
Parasit Vectors
January 2025
Melbourne Veterinary School, The University of Melbourne, Werribee, VIC, 3030, Australia.
Background: Gastrointestinal parasites such as nematodes and coccidia are responsible for significant economic losses in the goat industry globally. An indiscriminate use of antiparasitic drugs, primarily registered for use in sheep and cattle, in goats has resulted in drug-resistant gastrointestinal parasites. Very little is known about the gastrointestinal parasite control practices used by Australian dairy goat farmers that are pivotal for achieving sustainable control of economically important parasites.
View Article and Find Full Text PDFAbsolute eosinophil count and expression analyses of cytokine genes in Haemonchus contortus resistant Malpura sheep: Role of TH1/TH2 cytokine dichotomy.
Vet Parasitol Reg Stud Reports
January 2025
Animal Genetics and Breeding Division, ICAR-Central Sheep and Wool Research Institute, Avikanagar 304 501, Rajasthan, India.
A strong Th2-type immune response against Haemonchus contortus infection in genetically resistant sheep provide immunity. The objective of present study was to correlate mean faecal egg counts (FECs), absolute eosinophil counts and Th1/Th2 gene expression in resistant (R) and susceptible (S) Malpura sheep. In spite of no anthelmintic treatment in R line, on majority of the months, mean FECs remained significantly (P < 0.
View Article and Find Full Text PDFEgg reappearance periods associated with anthelmintic treatments given to horses in winter and summer over two years.
Vet Parasitol Reg Stud Reports
January 2025
Tāwharau Ora - School of Veterinary Science, Massey University, Private Bag 11222, Palmerston North 4410, New Zealand.
Shortened egg reappearance periods (ERP) have been seen as an early warning of anthelmintic resistance development in cyathostomins in horses. The hypothesis has been that in these instances, efficacy against egg laying adult cyathostomins remains high, but a decline in activity against later larval stages leads to the earlier resumption of egg shedding after treatment. In this study using a single herd of horses we investigated the ERP of a number of commonly used equine anthelmintics and examined whether ERP might show seasonal variation between winter and summer.
View Article and Find Full Text PDFFirst report of anthelmintic resistance among sheep in six farms from three governorates in Jordan.
Vet Parasitol Reg Stud Reports
January 2025
Department of Basic Medical Veterinary Sciences, Jordan University of Science & Technology, Irbid, Jordan.
This study aimed to identify the presence of gastrointestinal nematode populations resistant to albendazole, levamisole, and ivermectin in six farms located in three regions of Jordan (Irbid, Mafraq, and Ma'an). Infected sheep (40 per farm) with at least 100 eggs per gram were randomly divided into four groups (10 animals per group). Three groups were treated with ivermectin, albendazole, or levamisole while the fourth group was used as a negative control group.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!