A N-heterocyclic olefin (NHO), a terminal alkene selectively activates aromatic C-F bonds without the need of any additional catalyst. As a result, a straightforward methodology was developed for the formation of different fluoroaryl-substituted alkenes in which the central carbon-carbon double bond is in a twisted geometry.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7317942 | PMC |
http://dx.doi.org/10.1002/chem.202000276 | DOI Listing |
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