Romania has drastically improved an array of health indicators in recent years, including maternal mortality rates, which decreased from 1990 to 2015, but the mortality rates are still high, ranking among the first in Europe. Preeclampsia and eclampsia constitute one of the primary causes of maternal death in the country. The study was conducted from early January to the end of February 2019 to assess the current state of resident physicians' and midwives' knowledge of preeclampsia and eclampsia reflected in their practice at a clinical hospital in southern Romania. Self-administered questionnaires were used for data collection. Most of the investigated resident physicians and midwives (87.5%) answered correctly regarding the correct definition of preeclampsia. The first choice of procedure for the patient with preeclampsia (vaginal delivery or C-section) was chosen correctly by only 37.5% of the participants. Regarding the correct identification of the necessary paraclinical tests used for women with suspected preeclampsia, 58.3% of the participants answered correctly. As far as the correct identification of the possible risks of dexamethasone administration to mothers is concerned, only 29.2% of the participants answered correctly. Also, 58.3% of the participants answered correctly regarding the correct identification of contraindicated uterotonic drugs for women with diagnosed hypertension. Resident physicians and midwives are aware of pregnancy complications, but they hold limited knowledge specific to pregnancy complications as preeclampsia and eclampsia. It is imperative to promote studies to evaluate the impact of enhancing their training to include additional content related to the early detection and management of preeclampsia and eclampsia.
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http://dx.doi.org/10.25122/jml-2019-0130 | DOI Listing |
Am J Obstet Gynecol MFM
January 2025
Instituto de Medicina Integral Prof. Fernando Figueira (IMIP), Recife, Pernambuco, Brazil.
Background: Preeclampsia is a major hypertensive disorder of pregnancy, which may lead to severe complications, particularly in the first two weeks of the postpartum period. During the postpartum period, blood pressure levels remain high, often increasing to levels higher than those experienced during pregnancy. Furosemide, a fast-acting diuretic, reduces the intravascular volume overload and may represent an alternative to accelerate the normalization of blood pressure levels.
View Article and Find Full Text PDFJ Physiol
January 2025
Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK.
The mechanisms that drive placental dysfunction in pregnancies complicated by hypoxia and fetal growth restriction remain poorly understood. Changes to mitochondrial respiration contribute to cellular dysfunction in conditions of hypoxia and have been implicated in the pathoaetiology of pregnancy complications, such as pre-eclampsia. We used bespoke isobaric hypoxic chambers and a combination of functional, molecular and imaging techniques to study cellular metabolism and mitochondrial dynamics in sheep undergoing hypoxic pregnancy.
View Article and Find Full Text PDFPan Afr Med J
January 2025
Service de Gynéco-Obstérique de l'Hôpital de l'Amitié Tchad-Chine, Ndjamena, Tchad.
Introduction: arterial hypertension (AH) may persist beyond three months postpartum after preeclampsia, increasing the long-term risk of cardiovascular complications. The purpose of this study is to describe the epidemiological aspects and factors associated with persistent hypertension following preeclampsia.
Methods: we conducted a longitudinal descriptive study, from January 2022 to June 2023.
Int J Reprod Biomed
November 2024
Department of Obstetrics and Gynecology, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Background: Noninvasive perinatal testing is a new method of screening for aneuploidy called cell-free DNA (cfDNA). Fetal fraction (FF) plays a crucial role in assessing the reliability of aneuploidy detection through noninvasive perinatal testing.
Objective: We aimed to investigate the association between the amount of FF in cfDNA testing and adverse pregnancy outcomes.
Metabolomics
January 2025
Center for Child, Adolescent and Maternal Health Research, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
Introduction: Preeclampsia (PE) is a common vascular pregnancy disorder affecting maternal and fetal metabolism with severe immediate and long-term consequences in mothers and infants. During pregnancy, metabolites in the maternal circulation pass through the placenta to the fetus. Meconium, a first stool of the neonate, offers a view to maternal and fetoplacental unit metabolism and could add to knowledge on the effects of PE on the fetus and newborn.
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