Ventilator-associated tracheobronchitis (VAT) is an infection commonly affecting mechanically ventilated intubated patients. Several studies suggest that VAT is associated with increased duration of mechanical ventilation (MV) and length of intensive care unit (ICU) stay, and a presumptive increase in healthcare costs. Uncertainties remain, however, regarding the cost/benefit balance of VAT treatment. The aim of this narrative review is to discuss the two fundamental and inter-related dilemmas regarding VAT, i.e., (i) how to diagnose VAT? and (ii) should we treat VAT? If yes, should we treat all cases or only selected ones? How should we treat in terms of antibiotic choice, route, treatment duration?
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| http://dx.doi.org/10.3390/antibiotics9020051 | DOI Listing |
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Article Synopsis
- - The study aims to categorize respiratory infections in ventilated children, focusing on outcomes like the duration of mechanical ventilation and hospital stays, given the ongoing use of terms like ventilator-associated pneumonia (VAP) and tracheobronchitis in clinical practice.
- - Conducted across 15 Pediatric Intensive Care Units, the research analyzed data from 391 ventilated children, finding that the average hospital stay was 21 days with a mortality rate of 5.9%. Of the respiratory infections documented, 29.3% were classified as VAP and 70.7% as ventilator-associated tracheobronchitis (VAT).
- - Infections following ventilator-associated event (VAE) criteria led to
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