Central alveolar hypoventilation syndrome has been known for decades as Ondine's curse. It was named as such after a German myth. Although most of the stories resemble one another, word of mouth has led to misinterpretation of this tale among the medical community. The present paper reviews the original narrative, its characters, and how it is linked to the most relevant aspects of the disease.
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http://dx.doi.org/10.1590/0004-282X20190162 | DOI Listing |
Respirol Case Rep
December 2024
Division of Critical Care Medicine, Department of Internal Medicine National Cheng Kung University Hospital Tainan Taiwan.
Anti-Hu antibody-related paraneoplastic neurologic syndrome (PNS), a rare disease primarily associated with small cell lung carcinoma, is characterized by diverse neurologic manifestations. Central sleep apnea, although rare, is specific to anti-Hu antibody-related PNS. Herein, we present a case of out-of-hospital cardiac arrest attributed to hypercapnic central sleep apnea and detail the subsequent workup that revealed anti-Hu brainstem encephalitis.
View Article and Find Full Text PDFeNeurologicalSci
March 2024
LSUHSC Neurology Residency Program, United States of America.
Central hypoventilation syndrome (CHS) is a rare condition resulting from damage to the respiratory centers in the central nervous system (CNS). It can be congenital or acquired and can cause hypoventilation, inadequate gas exchange, and respiratory failure, often during sleep but sometimes even while awake. CHS can lead to respiratory failure and life-threatening complications if not identified promptly.
View Article and Find Full Text PDFCase Rep Surg
September 2023
Department of Neurosurgery, Al Tadawi Specialty Hospital, Dubai, UAE.
Ondine's curse is a rare condition in which breathing is preserved while awake, but there is absence of autonomic control of ventilation. It is a potentially fatal complication that may result rarely from surgery in posterior fossa in area close to respiratory centers. We describe a patient with posterior fossa hemangioblastoma who underwent subtotal resection via telovelar approach and developed acquired Ondine's curse postoperatively.
View Article and Find Full Text PDFFront Neurol
August 2023
Department of Critical Care Medicine, University of Pittsburgh Medical Center, Pittsburgh, PA, United States.
Introduction: Ondine's curse is a rare respiratory disorder that is characterized by central alveolar hypoventilation (CAH) during sleep. It is most commonly congenital. However, it can also be acquired very rarely.
View Article and Find Full Text PDFJ Neurosurg Case Lessons
May 2023
Departments of1Neurological Surgery.
Background: The complexity of posterior fossa surgery can often lead to rare complications due to the anatomy involved. Vestibular schwannoma resection is a common pathology in the posterior fossa, often requiring surgical intervention. Given the proximity of this space to the brainstem, cranial nerve VII/VIII complex, and posterior inferior cerebellar artery (PICA), neurovascular complications are not infrequent.
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