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http://dx.doi.org/10.1016/j.jdcr.2019.12.002 | DOI Listing |
J Vis Exp
August 2024
State Key Laboratory of Environmental and Biological Analysis, Department of Chemistry, Hong Kong Baptist University; Guangdong-Hong Kong-Macao Joint Laboratory for Contaminants Exposure and Health, School of Environmental Science and Engineering, Institute of Environmental Health and Pollution Control, Guangdong University of Technology;
JMIR Public Health Surveill
July 2024
Department of Emergency Medicine, Hanyang University College of Medicine, Seoul, Republic of Korea.
Background: The alcohol-induced facial flushing phenotype (flushing) is common among East Asians. Despite a small intake of alcohol, they experience heightened levels of acetaldehyde, a group-1 carcinogen, which, in turn, causes unpleasant symptoms such as redness, acting as a robust protective mechanism against consuming alcohol. However, some individuals with this genetic trait exhibit weakened alcohol restraint, which increases the risk of developing alcohol-related cancers, such as esophageal and head or neck cancer, by several times.
View Article and Find Full Text PDFInt J Mol Sci
April 2024
Department of Anatomy, Cell Biology and Zoology, Faculty of Sciences, University of Extremadura, 06006 Badajoz, Spain.
Alcohol, a widely consumed drug, exerts significant toxic effects on the human organism. This review focuses on its impact during fetal development, when it leads to a spectrum of disorders collectively termed Fetal Alcohol Spectrum Disorders (FASD). Children afflicted by FASD exhibit distinct clinical manifestations, including facial dysmorphism, delayed growth, and neurological and behavioral disorders.
View Article and Find Full Text PDFCureus
October 2023
Dermatology, Kaiser Permanente Los Angeles Medical Center, Los Angeles, USA.
Flush reactions can be incited by various factors including inherent mutation, drugs, and diseases. A medication that is commonly used in dermatology but less associated with alcohol-induced facial flushing is topical tacrolimus. We present the case of a 44-year-old man experiencing this phenomenon on a distant, non-application site and a review of cases published in the literature.
View Article and Find Full Text PDFAddict Biol
December 2023
Department of Psychology, Carnegie Mellon University, Pittsburgh, PA, USA.
Alcohol has been linked to both positive (e.g., sociability) and negative (e.
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