Occurrences of microorganic pollutants in the Kumho River by a comprehensive target analysis using LC-Q/TOF-MS with sequential window acquisition of all theoretical fragment ion spectra (SWATH).

In this study, simultaneous identification and semi-quantification of hundreds of micropollutant compounds, including pharmaceutical and personal care products (PPCPs) and pesticides were performed in river and effluent samples from the Kumho River Basin using liquid chromatography quadrupole time-of-flight mass spectrometry (LC-Q-TOF/MS) with sequential window acquisition of all theoretical fragment ion spectra (SWATH). In total, 85 compounds (29 pesticides and 56 PPCPs) were identified. The highest proportions of PPCP residues were detected in the downstream area of the Kumho River, close to the central city. On the other hand, the highest proportions of pesticide residues were observed upstream, near agricultural land and golf courses. Additionally, the highly exposable chemicals were prioritized using a scoring and ranking system based on their concentration and detection frequency. Thus, 20 compounds (7 pesticides and 13 PPCPs) with scores of 200 or higher were defined as highly exposable compounds in Kumho River basin.