We have synthesized a turn-on fluorescent probe, termed NB4OH, to detect cellular hypochlorite. NB4OH is mainly localized in the endoplasmic reticulum and detects ClO- in foam cells. The fluorescence change of the probe was explained by theoretical calculation as a PET process. The probe holds great promise for application in biomedical research, including atherosclerosis research.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1039/d0cc00090f | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Background: Vascular endothelial cell-derived exosomes are thought to mediate disease progression by regulating macrophage polarization. However, its mechanism in diabetes mellitus (DM)-related atherosclerosis (AS) progress is unclear.
Methods: High-glucose (HG) and oxLDL were used to induce human cardiac microvascular endothelial cells (HCMECs) to mimic DM-related AS model.
Floralozone attenuates atherosclerotic vascular injury by regulating AMPKα/SREBP-1c pathway and down-regulating miR-33-5p.
Eur J Nutr
January 2025
College of Pharmacy, Sanquan College of Xinxiang Medical University, Xinxiang, 453003, China.
Background: Severe disruption of lipid metabolism in vivo is one of the central mechanisms in the development of atherosclerotic vascular injury (AVI). Reverse cholesterol transport (RCT) plays a pivotal role in eliminating excess cholesterol, preventing lipid deposition in the aorta, and reducing plaque formation associated with AVI. Floralozone (FL) reduces endothelial cell injury in AVI rats by regulating sphingosine-1-phosphate (S1P) expression.
View Article and Find Full Text PDFElectrochemical Dechlorination of Gaseous Trichloroethylene to Nonchlorinated Value-Added Products Using a Cu/Ni Alloy Electrode with a Gel Membrane Interface.
ACS Appl Mater Interfaces
January 2025
Department of Environmental Engineering, Seoul National University of Science and Technology, Seoul 01811, Republic of Korea.
Trichloroethylene (TCE) is widely used in various industrial applications, leading to significant environmental and public health concerns due to its toxicity and persistence. Current nonthermal liquid-phase TCE treatment methods, including electrochemical processes, typically produce liquid byproducts that require additional separation steps, limiting their efficiency. To overcome these challenges, this study introduces an innovative electrochemical approach for the direct conversion of TCE gas into less harmful gaseous products, utilizing a Cu/Ni alloy 3D foam electrode integrated with a poly(vinyl alcohol) (PVA)-sodium polyphosphate (SPP) gel membrane system.
View Article and Find Full Text PDFInfluence of Structural Optimization on the Physical Properties of an Innovative FDM 3D Printed Thermal Barrier.
Materials (Basel)
December 2024
Department of Energy Conversion Engineering, Faculty of Mechanical and Power Engineering, Wroclaw University of Science and Technology, 27 Wybrzeze Wyspianskiego Street, 50-370 Wroclaw, Poland.
This article describes an innovative thermal insulation barrier in the form of a sandwich panel manufactured using 3D FDM printing technology. The internal structure (core structure) of the barrier is based on the Kelvin foam model. This paper presents the influence of the parameters (the height h and the porosity P of a single core cell) of the barrier on its properties (thermal conductivity, thermal resistance, compressive strength, and quasi-static indentation strength).
View Article and Find Full Text PDFEffect of Chemical Structure and Apparent Density of Rigid Polyurethane Foams on the Properties of Their Chemical Recycling Products.
Materials (Basel)
December 2024
Faculty of Chemical Engineering and Technology, Cracow University of Technology, Warszawska 24, 31-155 Kraków, Poland.
The aim of this work was to synthesize polyurethane foams based on petrochemical polyols and biopolyols with specific apparent densities (40, 60, 80, 100, and 120 kg/m), test their properties, glycolyze them, and finally analyze each glycolyzed product. The petroleum-based foams, used as reference foams, and the bio-based foams underwent a series of standard tests to define their properties (the content of closed cells 20-95%, compressive strength 73-1323 kPa, thermal conductivity 24-42 mW/m∙K, brittleness 4.6-82.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!