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| http://dx.doi.org/10.1161/JAHA.119.015502 | DOI Listing |
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The complex role of cardiovascular imaging in viability testing.
Prog Cardiovasc Dis
January 2025
Division of Cardiovascular Medicine, Department of Medicine, University of Virginia, Charlottesville, Virginia, USA. Electronic address:
Myocardial viability assessment is used to determine if chronically dysfunctional myocardium may benefit from coronary revascularization. Cardiac magnetic resonance with late gadolinium enhancement is the current gold standard for visualizing myocardial scar and provides valuable insight into myocardial viability. Viability assessments can also be made with Cardiac Positron Emission Tomography, Echocardiography, Single Photon Emission Tomography, and Cardiac Computed Tomography with each having advantages and disadvantages.
View Article and Find Full Text PDFThe Relationship Between the Type of ST-Segment Elevation in Acute Anterior Wall Myocardial Infarction and Left Ventricular Ejection Function.
Cureus
November 2024
Internal Medicine Department, Shalamar Hospital, Lahore, PAK.
Introduction: Acute anterior wall myocardial infarction (AWMI), when presenting with ST-segment elevation on an electrocardiogram (ECG), represents a form of ST-elevation myocardial infarction (STEMI) caused by a significant reduction in coronary blood flow to the heart muscle. The shape of the ST-segment elevation, whether it is concave, convex, or straight, has been associated with different levels of left ventricular ejection fraction (LVEF), which is an important indicator of cardiac function and prognosis.
Objective: To investigate the relationship between the type of ST-segment elevation on ECG and LVEF measured 48 hours after the onset of myocardial infarction in patients with AWMI.
Detection of Hibernating Myocardium: A Gate Keeper in Decision Making in Patients with Left Ventricular Dysfunction.
J Coll Physicians Surg Pak
October 2024
Department of Radiology, The Aga Khan University Hospital, Karachi, Pakistan.
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View Article and Find Full Text PDFPrediction of major arrhythmic outcomes in ischaemic cardiomyopathy: value of hibernating myocardium in positron emission tomography/computed tomography.
Eur Heart J Cardiovasc Imaging
December 2024
Department of Cardiology, University Heart Center, University Hospital Zurich, Raemistrasse 100, 8091 Zurich, Switzerland.
Aims: Known predictors of major arrhythmic events (MAEs) in patients with ischaemic cardiomyopathy (ICM) include previous MAE and left ventricular ejection fraction (LVEF) ≤ 35%. Myocardial scars detected by perfusion imaging in ICM have been linked to MAE, but the prognostic significance of hibernating myocardium (HM) is unclear. The objective was to predict MAEs from combined 13N-ammonia (NH3) and 18F-fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) in ICM.
View Article and Find Full Text PDFMetabolomics of repetitive myocardial stunning in chronic multivessel coronary artery stenosis: Effect of non-selective and selective β1-receptor blockers.
J Physiol
July 2024
Knight Cardiovascular Institute, Oregon Health and Science University, Portland, OR, USA.
Article Synopsis
- Chronic coronary artery stenosis can cause myocardial dysfunction without heart attacks, often due to repetitive stunning or hibernation.
- A study using metabolomics on dogs showed that β-blockers like carvedilol and metoprolol can help improve heart function and metabolism in damaged tissues, particularly by influencing mitochondrial function.
- Carvedilol had more positive effects on recovery and mitochondrial health than metoprolol, suggesting that different β-blockers can have different impacts on heart health.
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