Merkel cell carcinoma (MCC) of the skin is a rare but aggressive cutaneous neuroendocrine-derived malignancy that predominantly affects elderly white males. The presence of distant nodal metastases significantly impacts survival. Typical metastatic sites of MCC are liver, bone, brain and skin. Gastrointestinal metastases are uncommon and small bowel is the most common site followed by stomach. We report a case of symptomatic MCC jejunal metastasis.

Download full-text PDF

Source

Publication Analysis

Top Keywords

jejunal metastasis
8
merkel cell
8
cell carcinoma
8
metastasis merkel
4
carcinoma case
4
case report
4
report merkel
4
carcinoma mcc
4
mcc skin
4
skin rare
4

Similar Publications

Background: Sarcomatoid carcinoma of the small bowel is an exceedingly rare gastrointestinal tumor characterized by a biphasic cellular pattern of epithelioid and mesenchymal-like cells. Due to its rarity and non-specific clinical presentation, it is frequently misdiagnosed, and there is a lack of standardized management guidelines. We report a case of multiple sarcomatoid carcinoma of the small intestine, presenting initially with gastrointestinal perforation.

View Article and Find Full Text PDF

Canine extraskeletal osteosarcomas are mesenchymal, osteoid producing tumors that can arise in soft tissues without initial involvement of the bones. An 8-year-old intact male Beagle dog presented with anorexia, abdominal pain, intermittent vomiting and melena. The patient had a history of recurrent ingestion of cotton based-toy fragments, but no prior surgical procedures involving the abdominal cavity.

View Article and Find Full Text PDF

A 26-year-old male presented to a hospital with complaints of hemoptysis and right scrotal swelling. Computed tomography (CT) revealed right testicular swelling, multiple lung metastases, and small intestinal wall thickening. The patient's β-human chorionic gonadotropin, alpha-fetoprotein, lactate dehydrogenase, and hemoglobin levels were 103.

View Article and Find Full Text PDF
Article Synopsis
  • A 60s male patient diagnosed with advanced gastric cancer (with pyloric stenosis and enlarged lymph nodes) experienced significant tumor reduction after two courses of chemotherapy before surgery.
  • He underwent laparoscopic gastric jejunal bypass followed by distal gastrectomy and para-aortic lymph node dissection, with positive surgical results and no further tumor growth observed.
  • After the operation, he received a year of adjuvant chemotherapy and has remained recurrence-free for 1.5 years, highlighting the effectiveness of preoperative treatment for this condition.
View Article and Find Full Text PDF

The consumption of high-fat diets (HFD) and an imbalance in gut microbiome are linked to obesity. However, the intricate connection between them and the underlying mechanisms involved in lipid digestion and absorption remain largely unclear. This study shows that after 12 weeks of HFD feeding, mice exhibit two distinct metabolic phenotypes with significant differences in gut microbiota composition.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!