AI Article Synopsis
- Ten patients with untreated juvenile periodontitis (JP) were studied for their free oxygen radical generation using luminol enhanced chemiluminescence.
- Eight patients still showed heightened chemiluminescence (CL) responses after treatment when their PMN cells were stimulated, compared to healthy controls.
- The increased CL in PMN cells from JP patients is primarily due to inherent factors in their cells, rather than external serum factors from untreated patients.
Article Abstract
Ten patients with untreated juvenile periodontitis (JP) showing an increased generation rate of free oxygen radicals from their peripheral polymorphonuclear neutrophils (PMN) as measured by luminol enhanced chemiluminescence (CL) were rechecked after treatment. The PMN cells from eight patients still reacted with higher CL after stimulation with Staph. aureus opsonized with autologous serum when related to pair-matched controls. The increased CL was not caused by adsorption of serum factors from untreated JP patients when assayed with healthy PMN cells. The increased CL found in peripheral PMN cells from patients with JP thus depends very little on the disease activity.
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| http://dx.doi.org/10.1111/j.1600-0722.1988.tb01577.x | DOI Listing |
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