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Lack of a relationship between plasma fibroblast growth factor-23 and phosphate utilization in young chicks.
Poult Sci
April 2019
Department of Animal Science, The Pennsylvania State University, University Park, PA 16802, USA.
Fibroblast growth factor 23 (FGF-23) is proposed to be the hormone that controls phosphate (P) homeostasis in chickens. This study was initiated to investigate the effect of feeding young chicks diets that were either adequate (0.45%) or marginal (0.
View Article and Find Full Text PDFBone sialoprotein keratan sulfate proteoglycan (BSP-KSPG) and FGF-23 are important physiological components of medullary bone.
Comp Biochem Physiol A Mol Integr Physiol
April 2016
Department of Animal Science, The Pennsylvania State University, University Park, PA, United States. Electronic address:
Medullary bone is a specialized bone found in the marrow cavity of laying birds. It provides a significant contribution to the calcium supply for egg shell formation. Medullary bone is distinguished from cortical bone by the presence of large amounts of a keratan sulfate proteoglycan (KSPG).
View Article and Find Full Text PDFEffects of strontium on bone strength, density, volume, and microarchitecture in laying hens.
J Bone Miner Res
November 2006
Department of Nutritional Sciences, Pennsylvania State University, University Park, Pennsylvania, USA.
Article Synopsis
- Strontium supplementation in laying hens showed positive effects on bone metrics like bone mineral density (BMD) and bone mineral content (BMC), enhancing bone volume and mechanical properties.
- The study involved administering varying doses of strontium over 11 months to examine its impact on bone health, using techniques like DXA and microCT for measurement.
- While strontium improved bone structure and strength, it did not change the estimated material properties of the bone tissue nor affect calcium and phosphorus levels in the hens.
Characterization of the non-collagenous proteins in avian cortical and medullary bone.
Comp Biochem Physiol B Biochem Mol Biol
April 2005
Department of Poultry Science, 205 William L. Henning Building, The Pennsylvania State University, University Park, PA 16802, USA.
Northern blotting, RT-PCR, and Western blotting techniques were used to characterize the matrix constituents of avian cortical and medullary bone. Extracts of bone tissue were found to contain multiple isoforms of bone sialoprotein (BSP), osteopontin (OPN), osteonectin (ON), osteocalcin (OC), and dentin matrix protein-1 (DMP-1). Only single transcripts were observed with Northern blotting; therefore it was concluded that the isoforms were due to differences in post-translational modifications.
View Article and Find Full Text PDFShort-term zinc deficiency inhibits chondrocyte proliferation and induces cell apoptosis in the epiphyseal growth plate of young chickens.
J Nutr
April 2002
Department of Poultry Science, The Pennsylvania State University, University Park, PA 16802-3501, USA.
The purpose of this study was to investigate the effect of zinc deficiency on chondrocyte proliferation, differentiation and apoptosis in the epiphyseal growth plate of juvenile chickens. Newly hatched broiler chickens were fed either a low zinc (10 mg/kg diet) or a zinc-adequate (68 mg/kg diet) soy protein-based purified diet. Cell proliferation in the growth plate was evaluated with bromodeoxyuridine (BrdU) labeling.
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