: A history of heparin hypersensitivity in patients undergoing cardiopulmonary bypass surgery poses the dilemma of which anticoagulant to use. Here, we report the successful use of a heparin challenge test in a 66-year-old female candidate for coronary artery bypass graft surgery with a past medical history of enoxaparin type I hypersensitivity after pulmonary embolism. Challenge and desensitization protocols are effectively used for essential antibiotics in patients with severe infections and/or allergies, or patients with aspirin intolerance requiring revascularization for coronary disease. A successful use of desensitization protocols to unfractionated heparin has been previously described in four patients undergoing cardiac surgery with various schemes. However, our case report indicates that a challenge test may also offer a quick, safe and effective approach in patients with a history of hypersensitivity reactions to heparin with inconclusive diagnostic tests and/or whenever the use of alternative heparins is tricky.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1097/MBC.0000000000000883 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Design and implementation of the fractional-order controllers for a real-time nonlinear process using the AGTM optimization technique.
Sci Rep
December 2024
School of Electrical Engineering, Vellore Institute of Technology, Chennai, 600127, India.
Spherical tanks have been predominantly used in process industries due to their large storage capability. The fundamental challenges in process industries require a very efficient controller to control the various process parameters owing to their nonlinear behavior. The current research work in this paper aims to propose the Approximate Generalized Time Moments (AGTM) optimization technique for designing Fractional-Order PI (FOPI) and Fractional-Order PID (FOPID) controllers for the nonlinear Single Spherical Tank Liquid Level System (SSTLLS).
View Article and Find Full Text PDFExperimental evidence of high tick infestation limiting chick growth and survival in a colonial seabird.
Sci Rep
December 2024
MARE - Marine and Environment Sciences Centre/ARNET - Aquatic Research Network, Ispa - Instituto Universitário, Lisboa, Portugal.
While numerous studies have established correlations between parasite load and negative effects on their hosts, establishing causality is more challenging because parasites can directly compromise host condition and survival or simply opportunistically thrive on an already weakened host. Here, we evaluated whether Ixodes uriae, a widespread seabird tick, can cause a decrease in growth parameters (body mass, bill length and growth rates) and survival of chicks of a colonially seabird, the black-browed albatross (Thalassarche melanophris) breeding on New Island (West Falkland). To investigate this, we daily removed the ticks from 28 randomly selected chicks during their first 14 days of life (treated chicks) and compared their growth and survival with 49 chicks of a control group.
View Article and Find Full Text PDFUse of large language models as artificial intelligence tools in academic research and publishing among global clinical researchers.
Sci Rep
December 2024
Department of Dermatology, Niazi Hospital, Lahore, Pakistan.
With breakthroughs in Natural Language Processing and Artificial Intelligence (AI), the usage of Large Language Models (LLMs) in academic research has increased tremendously. Models such as Generative Pre-trained Transformer (GPT) are used by researchers in literature review, abstract screening, and manuscript drafting. However, these models also present the attendant challenge of providing ethically questionable scientific information.
View Article and Find Full Text PDFBioinspired origami-based soft prosthetic knees.
Nat Commun
December 2024
Department of Advanced Manufacturing and Robotics, College of Engineering, Peking University, Beijing, China.
Prosthetic knees represent a prevalent solution for above-knee amputation rehabilitation. However, satisfying the ambulation requirements of users while achieving their comfort needs in terms of lightweight, bionic, shock-absorbing, and user-centric, remains out of reach. Soft materials seem to provide alternative solutions as their properties are conducive to the comfort aspect.
View Article and Find Full Text PDFObservation of non-Hermitian boundary induced hybrid skin-topological effect excited by synthetic complex frequencies.
Nat Commun
December 2024
Department of Physics, The Hong Kong University of Science and Technology, Hong Kong, China.
The hybrid skin-topological effect (HSTE) has recently been proposed as a mechanism where topological edge states collapse into corner states under the influence of the non-Hermitian skin effect (NHSE). However, directly observing this effect is challenging due to the complex frequencies of eigenmodes. In this study, we experimentally observe HSTE corner states using synthetic complex frequency excitations in a transmission line network.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!