• An overview of the general evaluation of undifferentiated right atrial masses. • Multimodality imaging workup and surveillance of intracardiac masses. • Value of noninvasive imaging for surveillance/prognostication of cardiac masses. • Atrial thrombi as an underappreciated complication of indwelling central catheters. • A review of cardiac malignancies and rare metastatic potential of Ewing's sarcoma.
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http://dx.doi.org/10.1016/j.case.2019.07.006 | DOI Listing |
Nat Commun
November 2024
Institut de Génétique et de Biologie Moléculaire et Cellulaire, Integrated Structural Biology Department, Illkirch, France.
The ribosome maturation factor Rea1 (or Midasin) catalyses the removal of assembly factors from large ribosomal subunit precursors and promotes their export from the nucleus to the cytosol. Rea1 consists of nearly 5000 amino-acid residues and belongs to the AAA+ protein family. It consists of a ring of six AAA+ domains from which the ≈1700 amino-acid residue linker emerges that is subdivided into stem, middle and top domains.
View Article and Find Full Text PDFClin Transl Oncol
November 2024
Hospital Universitario 12 de Octubre, IMAS 12, UCAM, Madrid, Spain.
Testicular germ cell tumors are the most common tumors in adolescent and young men. They are curable malignancies that should be treated with curative intent, minimizing acute and long-term side effects. Inguinal orchiectomy is the main diagnostic procedure, and is also curative for most localized tumors, while patients with unfavorable risk factors for recurrence, or those who are unable or unwilling to undergo close follow-up, may require adjuvant treatment.
View Article and Find Full Text PDFPLoS One
June 2024
Department of Mathematics and Mechanics, Novosibirsk State University, Novosibirsk, Russia.
Currently, the primary factor indicating the necessity of an operation for an abdominal aortic aneurysm (AAA) is the diameter at its widest part. However, in practice, a large number of aneurysm ruptures occur before reaching a critical size. This means that the mechanics of aneurysm growth and remodeling have not been fully elucidated.
View Article and Find Full Text PDFCureus
May 2024
College of Medical and Dental Sciences, University of Birmingham, Birmingham, GBR.
Bilateral adrenal hyperplasia associated with primary lung cancer may arise from either an adrenocorticotropic hormone (ACTH)-dependent paraneoplastic syndrome or metastatic hyperplasia. Ectopic Cushing's syndrome manifests as a paraneoplastic syndrome characterized by the secretion of ACTH from malignant cells. This secretion can in turn overstimulate the adrenal cortex, resulting in adrenal cortical hyperplasia followed by hypercortisolism.
View Article and Find Full Text PDFEur J Cancer
May 2024
University Department of Medical Oncology, Inselspital, University Hospital, University of Bern, Bern, Switzerland. Electronic address:
Aims: To resolve the ongoing controversy surrounding the impact of teratoma (TER) in the primary among patients with metastatic testicular non-seminomatous germ-cell tumours (NSGCT).
Patients And Methods: Using the International Germ Cell Cancer Collaborative Group (IGCCCG) Update Consortium database, we compared the survival probabilities of patients with metastatic testicular GCT with TER (TER) or without TER (NTER) in their primaries corrected for known prognostic factors. Progression-free survival (5y-PFS) and overall survival at 5 years (5y-OS) were estimated by the Kaplan-Meier method.
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