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http://dx.doi.org/10.1093/af/vfz030 | DOI Listing |
Background: Post-menopausal women experience more severe muscular fatty infiltration, though the mechanisms remain unclear. The decline in estrogen levels is considered as a critical physiological alteration during post-menopause. Fibro/adipogenic progenitors (FAPs) are identified as major contributors to muscular fatty infiltration.
View Article and Find Full Text PDFSci Rep
January 2025
Clinical Department of Diabetology, Hypertension and Internal Diseases, Institute of Internal Diseases, Wroclaw Medical University, 213 Borowska St, Wroclaw, 50-556, Poland.
Oxidative stress is proven to increase cardiovascular risk and to diminish healthy life expectancy. Sleep bruxism (SB) is a prevalent masticatory muscle activity during sleep characterized by heterogeneous etiology and inadequately recognized pathophysiology. Recent theories have proposed a potential association between SB and oxidative stress.
View Article and Find Full Text PDFDiabetes
January 2025
Department of Geriatrics, Peking University Shenzhen Hospital, Shenzhen, China.
Insulin resistance, a hallmark of type 2 diabetes, accelerates muscle breakdown and impairs energy metabolism. However, the role of Ubiquitin Specific Peptidase 2 (USP2), a key regulator of insulin resistance, in sarcopenia remains unclear. Peroxisome proliferator activated receptor γ (PPARγ) plays a critical role in regulating muscle atrophy.
View Article and Find Full Text PDFWiad Lek
January 2025
DEPARTMENT OF GENERAL PATHOLOGY AND FORENSIC MEDICINE, COLLEGE OF MEDICINE, UNIVERSITY OF KUFA, KUFA, IRAQ.
Objective: Aim: To evaluate the expression levels of SOX-10 in tissues of bladder tumor and to prove the correlation between SOX-10 expression and clinicopathological characteristics of bladder tumors, including patient age, sex, tumor grade, and muscle invasion.
Patients And Methods: Materials and Methods: Forty formalin fixed paraffin embedded FFPE tissue blocks gathered by transurethral resection of bladder tumor are collected from teaching hospitals at Al-Najaf governorate. Those blocks were stained by hematoxylin and eosin.
Wiad Lek
January 2025
DEPARTMENT OF GENERAL PATHOLOGY AND FORENSIC MEDICINE, COLLAGE OF MEDICINE, UNIVERSITY OF KUFA, KUFA, IRAQ.
Objective: Aim: To analyze expression levels of GATA-3 in bladder tumor tissues and to prove a relation between expression of GATA-3 and clinicopathological characteristics of bladder tumors, including patient age, sex, tumor grade, and muscle invasion.
Patients And Methods: Materials and Methods: Forty formalin fixed paraffin embedded (FFPE) tissue blocks obtained from bladder tumor by transurethral resection are collected from teaching hospitals at Al-Najaf governorate. Those blocks are stained by using hematoxylin and eosin stain.
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