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Impact Of Open And Endovascular Caseload In Lower Limb Amputation In Portugal - An Analysis From 2000 To 2015.
Port J Card Thorac Vasc Surg
October 2024
Department of Surgery and Physiology, Cardiovascular R&D Unit, Faculdade de Medicina da Universidade do Porto, Portugal; Centro Hospitalar de Vila Nova de Gaia e Espinho, Vila Nova de Gaia, Portugal.
Objectives: Effective revascularization is the cornerstone of limb salvage in chronic limb threatening ischemia. In recent years, less invasive endovascular revascularization techniques have supplanted surgical bypass as the primary mode of revascularization. The real impact of this transition is being increasingly questioned.
View Article and Find Full Text PDFHUVECs-derived exosomes increase neovascularization and decrease limb necrosis in hindlimb ischemia.
Narra J
December 2024
Department of Cardiology and Vascular Medicine, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada, Yogyakarta, Indonesia.
Chronic limb-threatening ischemia (CLTI) is the most severe manifestation of peripheral arterial disease (PAD) and imposes a significantly high burden due to its high risk of mortality and amputation. Revascularization is the first-line treatment for CLTI; however, the amputation rate remains high, and approximately one-third of patients are not eligible for this treatment. Therefore, there is an urgent need for more effective therapeutic strategies.
View Article and Find Full Text PDFInfrainguinal bypass for limb salvage has comparable mortality and affords a better chance of home discharge than amputation among octogenarians.
J Vasc Surg
January 2025
The George Washington University Hospital, Department of Surgery, Washington, D.C., USA.
Background: Infrainguinal bypass for chronic limb-threatening ischemia (CTLI) in octogenarians is considered a high-risk procedure due to the presumed associated frailty of the patient population. However, the alternative which is major amputation may not be a better option. This study retrospectively compares the outcomes of bypass versus major amputation for functionally independent and partially dependent patients.
View Article and Find Full Text PDFAvailability of Great Saphenous Vein for Infrainguinal Bypass.
Eur J Vasc Endovasc Surg
January 2025
Department of Angiology and Vascular Surgery, University Hospital of Galdakao Usansolo, Bizkaia, Spain.
Behavioral health comorbidities in hospital outcomes post-lower extremity amputation in patients with type 1 and type 2 diabetes.
J Diabetes Complications
January 2025
Kansas College of Osteopathic Medicine, Kansas Health Science University, Wichita, KS, USA. Electronic address:
Peripheral artery disease leading to chronic limb threatening ischemia (CLTI) represents a significant concern for up to 11.0 % of patients with diabetes, often culminating in amputation of the affected limb. This retrospective cohort study explores frequency of comorbid behavioral health conditions (CBHCs) in patients with diabetes and hospital stay characteristics related to post-lower extremity amputation (LEA).
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