Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1667/RR00EG.1 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Multi-institutional analysis of stereotactic body radiotherapy for sarcoma pulmonary metastases: High rates of local control with favorable toxicity.
J Surg Oncol
October 2020
Department of Radiation Oncology, Massachusetts General Hospital, Boston, Massachusetts.
Background/objectives: Oligometastatic sarcoma pulmonary metastases (PM's) are traditionally treated with resection and/or chemotherapy. We hypothesize that stereotactic body radiotherapy (SBRT) is an effective, safe alternative to surgery that can achieve excellent local control (LC) with a favorable toxicity profile.
Methods: Patients treated with SBRT for sarcoma PM's from 2011 to 2016 at Massachusetts General Hospital and the University of Pennsylvania were included.
Understanding High-Dose, Ultra-High Dose Rate, and Spatially Fractionated Radiation Therapy.
Int J Radiat Oncol Biol Phys
July 2020
Department of Radiation Oncology, University of California-Irvine, Irvine, California. Electronic address:
The National Cancer Institute's Radiation Research Program, in collaboration with the Radiosurgery Society, hosted a workshop called Understanding High-Dose, Ultra-High Dose Rate and Spatially Fractionated Radiotherapy on August 20 and 21, 2018 to bring together experts in experimental and clinical experience in these and related fields. Critically, the overall aims were to understand the biological underpinning of these emerging techniques and the technical/physical parameters that must be further defined to drive clinical practice through innovative biologically based clinical trials.
View Article and Find Full Text PDFInfrared navigation system for light dosimetry during pleural photodynamic therapy.
Phys Med Biol
April 2020
Department of Radiation Oncology, University of Pennsylvania, Philadelphia, PA, United States of America.
Pleural photodynamic therapy (PDT) is performed intraoperatively for the treatment of microscopic disease in patients with malignant pleural mesothelioma. Accurate delivery of light dose is critical to PDT efficiency. As a standard of care, light fluence is delivered to the prescribed fluence using eight isotropic detectors in pre-determined discrete locations inside the pleural cavity that is filled with a dilute Intralipid solution.
View Article and Find Full Text PDFEvaluation of Light Fluence Distribution Using an IR Navigation System for HPPH-mediated Pleural Photodynamic Therapy (pPDT).
Photochem Photobiol
March 2020
Department of Radiation Oncology, University of Pennsylvania, Philadelphia, PA.
Uniform light fluence distribution for patients undergoing photodynamic therapy (PDT) is critical to ensure predictable PDT outcomes. However, current practice when delivering intrapleural PDT uses a point source to deliver light that is monitored by seven isotropic detectors placed within the pleural cavity to assess its uniformity. We have developed a real-time infrared (IR) tracking camera to follow the movement of the light point source and the surface contour of the treatment area.
View Article and Find Full Text PDFBiological Principles of Stereotactic Body Radiation Therapy (SBRT) and Stereotactic Radiation Surgery (SRS): Indirect Cell Death.
Int J Radiat Oncol Biol Phys
May 2021
Department of Radiation Oncology, University of Minnesota Medical School, Minneapolis, Minnesota.
Purpose: To review the radiobiological mechanisms of stereotactic body radiation therapy stereotactic body radiation therapy (SBRT) and stereotactic radiation surgery (SRS).
Methods And Materials: We reviewed previous reports and recent observations on the effects of high-dose irradiation on tumor cell survival, tumor vasculature, and antitumor immunity. We then assessed the potential implications of these biological changes associated with SBRT and SRS.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!