Background: This article gives an overview of severe and fulminant infections of the head and neck region. The focus is on the treatment, diagnostics and causes of abscesses, phlegmon and necrotizing fasciitis.
Objective: Despite guideline-conform treatment soft tissue infections of the head and neck can spread rapidly and be life-threatening.
Material And Methods: Analysis and discussion of basic research and expert recommendations, case reports.
Results: While purulent tonsillitis is the primary cause of severe bacterial soft tissue infections in children, dental infections are the leading cause in adults. The infections often spread along anatomic spaces and can extend into the brain or mediastinum and a hematogenic dissemination is also possible. Multiple operations and combined antibiotic treatment are often required as well as additional treatment, such as intubation, tracheotomy and dialysis. Late or early onset complications can occur and reconstructive measures might be necessary in addition to rehabilitation.
Conclusion: Severe bacterial soft tissue infections can be still life-threatening despite guideline-conform treatment and are associated with a high mortality especially in high-risk patients even with intensive medical care. They can lead to disfiguration and loss of function resulting in a greatly reduced quality of life. Rapid diagnostics and therapy are essential for successful treatment.
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http://dx.doi.org/10.1007/s00104-020-01121-x | DOI Listing |
J Surg Case Rep
January 2025
Department of Colorectal Surgery, Sydney Adventist Hospital, 185 Fox Valley Road, Wahroonga, Sydney, New South Wales 2076, Australia.
An 84-year-old lady presented with 1 day history of sudden onset generalized abdominal pain, fevers, and peritonism. Computed tomography was suggestive of a mid-small bowel perforation associated with a distal ovoid soft tissue density structure without pneumobilia. An urgent laparotomy demonstrated two areas of jejunal diverticula necrosis and perforation associated with a 3 cm luminal mass in the proximal ileum, and proximal small bowel dilatation.
View Article and Find Full Text PDFWorld J Clin Oncol
January 2025
Department of Hematology, The First Affiliated Hospital of Jishou University, Jishou 416000, Hunan Province, China.
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View Article and Find Full Text PDFExtreme Mech Lett
March 2025
Department of Mechanical Engineering, Stanford University, Stanford, CA 94305, USA.
Cutting soft materials on the microscale has emerging applications in single-cell studies, tissue microdissection for organoid culture, drug screens, and other analyses. However, the cutting process is complex and remains incompletely understood. Furthermore, precise control over blade geometries, such as the blade tip radius, has been difficult to achieve.
View Article and Find Full Text PDFCase Rep Dent
January 2025
Department of Surgical Sciences, Division of Conservative Dentistry and Endodontics, School of Dental Medicine, University of Cagliari, Cagliari, Italy.
This case report discusses the successful management of a deep palatal developmental groove associated with Stage III generalized Grade C periodontitis. Despite prior nonsurgical periodontal therapy, the disease progressed rapidly, necessitating further intervention. A comprehensive evaluation revealed generalized periodontitis with localized tooth-related predisposing factor due to a developmental groove in the vital upper left lateral incisor.
View Article and Find Full Text PDFJ Community Hosp Intern Med Perspect
January 2025
University Maryland Medical Center Midtown Campus, Department of Internal Medicine, USA.
is a rod-shaped, flagellated, non-lactose fermenting, gram negative bacterium, usually found in water and soil habitats. generally causes nosocomial infections in immunocompromised patients. Increased infection rates are seen in those patients with medical devices inserted, due to this organism's innate ability to attach to moist and inanimate objects.
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