Euro Surveill
1st Internal Medicine & Infectious Diseases Department, Hygeia General Hospital, Athens, Greece.
Published: January 2020
From September to October 2019, seven patients colonised or infected with a ceftazidime-avibactam (CZA)-resistant carbapenemase (KPC)-2-producing were detected in two intensive care units of a Greek general hospital. The outbreak strain was sequence type (ST)147 and co-produced KPC-2 and the novel plasmid-borne Vietnamese extended-spectrum β-lactamase (VEB)-25 harbouring a K234R substitution associated with CZA resistance. Epidemiological investigations revealed that the resistance was probably acquired by horizontal transmission independently from previous CZA exposure.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6988274 | PMC |
http://dx.doi.org/10.2807/1560-7917.ES.2020.25.3.2000028 | DOI Listing |
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