Discovering novel means of protection from harmful substances in toothpaste is essential due to its mass production, and frequent exposure to its ingredients by consumers. This method of safeguarding through discovery demonstrates toothpaste safety, which is at risk of being stifled by other commercial priorities. Among the ingredients in toothpaste that cause adverse effects is sodium lauryl sulphate (SLS). An understanding of this source and its effects therefore allows for investigating preventative strategies through the use of safer alternatives. Saponin, a naturally occurring chemical in several plant species was discovered to be an alternative compound that may parallel the effects of sodium lauryl sulphate, yet exude less ill effects. This article highlights the benefits of saponin and its presence in a heavily consumed and exported fruit in Jamaica (ackee, Blighia sapida). The possibility of extracting saponin from ackee, and its use in the toothpaste industry as an alternative to sodium lauryl sulphate are discussed. Through consideration of this alternative, the potential exists to improve the safety of toothpastes and consequently improve oral health.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1016/j.mehy.2020.109555 | DOI Listing |
Adv Wound Care (New Rochelle)
January 2025
Kenatha Scientific Consulting LLC, Fort Worth, Texas, USA.
SN514 is a thermolysin-like enzyme under development as a debrider. Preclinical and non-clinical studies supported a first in human healthy volunteer study to predict the need for protection of periwound skin. Pharmacologic activity testing compared digestion of collagen, fibrin, and elastin with relevant enzymes.
View Article and Find Full Text PDFSci Rep
January 2025
School of Chemical, Petroleum and Gas Engineering, Iran University of Science and Technology (IUST), P.O. Box 16844-13114, Tehran, Iran.
Surfactant chemistry can affect the phenolic foam (PF) properties by controlling the collision and combination of the created bubbles during foam production. The study was accomplished using two surfactant families, nonionic: polysorbate (Tween80) and anionic: sodium and ammonium lauryl sulfates (SLS30 and ALS70) and sodium laureth sulfate (SLES270) to manufacture PF foams. Tween80 and SLS30 resulted in foams with the lowest and highest densities, 20.
View Article and Find Full Text PDFToxicol Mech Methods
January 2025
Department of Pharmacology, Shri Vishnu College of Pharmacy, Vishnupur, Bhimavaram, Andhra Pradesh, India-534202.
The harmful by-product of paracetamol is known as N-Acetyl-p-benzoquinoneimine, (NAPQI). When paracetamol is given at therapeutic dosages or in excess, it undergoes Phase I metabolism in the liver via Cytochrome P-450 2E1 (CYP2E1), and then it produces NAPQI. Previous studies reported that a non-ionic surfactant known as Brij 35 (Polyoxyethylene lauryl ether) has been shown to be an effective inhibitor of CYP2E1 and P-glycoprotein (P-gp).
View Article and Find Full Text PDFAnal Methods
January 2025
Analytical Chemistry Department, Faculty of Pharmacy, Zagazig University, Zagazig 44519, Egypt.
Hypertension and dyslipidemia are two of the most frequently co-occurring cardiovascular risk factors. The combined regimen of hydrochlorothiazide (HCTZ), rosuvastatin (ROS), and losartan (LOS) helped in the successful management of both conditions. This work's objective is to develop an eco-friendly, sensitive, simple, and reliable chromatographic method for the simultaneous estimation of HCTZ, ROS, and the LOS ternary mixture in their pure form, and pharmaceutical formulations.
View Article and Find Full Text PDFAdv Healthc Mater
January 2025
School of Chemistry and Molecular Engineering, East China Normal University, Shanghai, 200241, P. R. China.
Urinary catheters serve as critical medical devices in clinical practice. However, the currently used urinary catheters lack efficient antibacterial and lubricating properties, often leading to discomfort with patients and even severe urinary infections. Herein, a new strategy of supramolecular assembly and disassembly of chitosan (Cs) is developed that enables efficient antibacterial lubricous and biodegradable hydrogel urinary catheters.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!