Ovine babesiosis is an endemic tick-borne disease of small ruminants in the Middle East, European, and some African and Asian countries, including Turkey. This study assessed whether the endemic status of this disease was stable or instable, which is important for disease control efforts. For this aim, 4115 sheep blood samples were collected from 81 cities in the seven geographical regions of Turkey. The diagnosis of Babesia ovis was made using microscopic and serological techniques. Thin blood smears were prepared from anticoagulated venous blood. Serum samples were screened for specific antibodies using an enzyme-linked immunosorbent assay (ELISA) and indirect fluorescent antibody test (IFAT). Recombinant Babesia ovis secreted antigen 1 (rBoSA1) was used in the ELISA. The antigen slides used in the IFAT were prepared from the B. ovis-infected blood at a high level of parasitemia (5 %). The animals were divided into three groups according to their age: group I (one to six months), group II (6-12 months), and group III (older than one year). The endemic status of B. ovis was determined according to the inoculation rate (h value) calculations. Babesia spp. merozoites were observed in 40 (0.97 %) of the slides. Seropositivity rates were 29.89 % (1230/4115) and 49.16 % (2023/4115) by the ELISA and IFAT, respectively. According to the IFAT results, 31.7 %, 33.6 %, and 52.8 % of the animals were seropositive in groups I, II, and III, respectively. The inoculation rates of the animals indicated that the endemic status of ovine babesiosis was mostly instable throughout the country. Endemic stability was found only in group I from four regions (Central Anatolia, Eastern Anatolia, Aegean, and Mediterranean). Based on these results, the risk of clinical infection due to tick infestation was high when the maternal immunity and non-specific age resistance weakens or disappears. Thus, vaccination is needed to protect sheep against B. ovis infections in Turkey.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.vetpar.2020.109034 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
An epidemiological survey of bovine piroplasmosis in Kashgar, Xinjiang, China.
Parasitol Res
December 2024
College of Animal Science and Technology, Shihezi University, Shihezi, 832000, Xinjiang, China.
Piroplasmosis is an important tick-borne disease in several regions, and can lead to significant economic animal production losses. The current study aimed to systematically examine the incidence of bovine piroplasmosis in Kashgar, Xinjiang, to provide baseline data for the effective prevention and control of this disease among bovines in the region. A total of 1403 bovine blood samples from 12 sampling points were screened via PCR with universal Piroplasma primers targeting the 18S rRNA locus and specific Theileria annulata primers targeting the cytochrome b (COB) gene.
View Article and Find Full Text PDFExperimental infection of purebred Saanen goats high pathogenicity and virulence of Babesia aktasi.
PLoS Negl Trop Dis
December 2024
Department of Parasitology, Faculty of Veterinary Medicine, University of Fırat, Elazig, Turkey.
Small ruminant babesiosis remains a neglected disease despite causing significant economic losses to sheep and goat herds in many regions around the world. The pathogenesis and clinical manifestations of ovine babesiosis are well-known, but there is a lack of information regarding caprine babesiosis. Since the discovery of the first Babesia spp.
View Article and Find Full Text PDFAssessment of pathogenicity in goats: implications for transmission dynamics and host resistant.
Front Cell Infect Microbiol
November 2024
Department of Parasitology, Faculty of Veterinary Medicine, University of Firat, Elazig, Türkiye.
, commonly associated with ovine babesiosis, poses a significant threat to sheep health, often resulting in severe clinical manifestations and high mortality rates. However, the impact of on goats has remained uncertain, prompting us to investigate its pathogenicity in caprine hosts. Experimental infections using -infected blood inoculation and infected tick infestation, were conducted on spleen-intact (n=5) and splenectomized (n=5) goats.
View Article and Find Full Text PDFMitochondrial Genome Analysis of (Apicomplexa: Babesiidae) Endemic in Sheep in Türkiye.
Vet Sci
November 2024
Department of Parasitology, Faculty of Veterinary Medicine, University of Fırat, Elazig 23200, Türkiye.
Article Synopsis
- * It reveals that the genomes have a high sequence similarity with related species, indicating close evolutionary ties and emphasizing the importance of mitochondrial genes in understanding species relationships.
- * The research highlights the role of terminal inverted repeats in mitochondrial size variation and suggests that examining mitochondrial genomes could improve diagnostic and treatment approaches for babesiosis.
Detection of Babesia spp., and Theileria spp., in sheep across diverse provinces of Iran.
Vet Parasitol Reg Stud Reports
November 2024
Department of Parasite Vaccine Research and Production, Razi Vaccine and Serum Research Institute, Agricultural Research, Education and Extension Organization (AREEO), Karaj, Iran. Electronic address:
Article Synopsis
- * Out of 373 samples, 27% displayed piroplasm infections, predominantly from Theileria spp. (78 samples) and Babesia spp. (23 samples), with a molecular detection rate of 38%.
- * The main findings indicated that Theileria ovis was prevalent, while Babesia ovis was the primary cause of Babesiosis, highlighting the importance of molecular diagnostics for accurate identification, especially in co-infection scenarios.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!