Purpose: To report a series of 3 eyes of 3 children with congenital glaucoma receiving the XEN gel stent implant.
Patients And Methods: An interventional case series is reported.
Results: Three eyes underwent implantation of the gel stent. In 2 cases, the gel implant procedure was performed after failed trabeculotomy, while in the third eye, primary gel stent implantation was performed. One eye received 2 implants. Three procedures were performed via an ab interno approach while the fourth was performed ab externo. No device-related complications were observed. In all 3 eyes, intraocular pressure was controlled without the use of topical medications through 6 to 24 months of follow-up.
Conclusions: The gel stent implant can be safely used in children with congenital glaucoma and effectively lowers intraocular pressure in these eyes. This procedure is a viable follow-up to, or replacement for, traditional angle surgery in eyes with congenital glaucoma.
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http://dx.doi.org/10.1097/IJG.0000000000001453 | DOI Listing |
Am J Ophthalmol Case Rep
December 2024
Casey Eye Institute at Oregon Health and Science University, 515 SW Campus Dr., Portland, OR, 97239, USA.
This video demonstrates the novel "macaroni necklace" technique for removing a Xen gel stent. The technique allows for complete removal of the stent without the hydrated and soft pieces from tearing apart. In this case, the stent was the nidus for endophthalmitis, and complete removal is necessary for prevention of future infections.
View Article and Find Full Text PDFKorean J Ophthalmol
December 2024
Department of Ophthalmology, Institute of Vision Research, Severance Eye Hospital, Yonsei University College of Medicine, South Korea.
Materials (Basel)
November 2024
School of Materials Science and Engineering, Zhengzhou University, Zhengzhou 450001, China.
With the continuous progress of biomedical technology, biomaterial coatings play an important role in improving the performance of medical devices and promoting tissue repair and regeneration. The application of natural medicine to biological materials has become a hot topic due to its diverse biological activity, low toxicity, and wide range of sources. This article introduces the definition and classification of natural medicines, lists some common natural medicines, such as curcumin, allicin, chitosan, tea polyphenols, etc.
View Article and Find Full Text PDFJ Curr Glaucoma Pract
October 2024
Department of Ophthalmology, Hospital of San Severino Marche, AV3- Asur Marche, Macerata, Italy.
Ocul Immunol Inflamm
November 2024
Centre for Ophthalmology, University Hospital Tuebingen, Tuebingen, Germany.
Purpose: To investigate the long-term outcomes of XEN-45 implantation for glaucoma secondary to Fuchs uveitis syndrome (FUS), juvenile idiopathic arthritis (JIA)-related anterior uveitis and intermediate uveitis (IU).
Methods: This retrospective study evaluated 19 eyes with FUS, 10 eyes with JIA, and nine eyes with IU that underwent XEN-45 Gel Stent implantation. The primary outcome measure was 3-year surgical success, defined as a ≥20% reduction in intraocular pressure (IOP), with a target IOP of 6-21 mmHg.
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