Background: Lung cancer has become a major cause of cancer-related deaths. Detection of potentially malignant lung nodules is essential for the early diagnosis and clinical management of lung cancer. In clinical practice, the interpretation of Computed Tomography (CT) images is challenging for radiologists due to a large number of cases. There is a high rate of false positives in the manual findings. Computer aided detection system (CAD) and computer aided diagnosis systems (CADx) enhance the radiologists in accurately delineating the lung nodules.
Objectives: The objective is to analyze CAD and CADx systems for lung nodule detection. It is necessary to review the various techniques followed in CAD and CADx systems proposed and implemented by various research persons. This study aims at analyzing the recent application of various concepts in computer science to each stage of CAD and CADx.
Methods: This review paper is special in its own kind because it analyses the various techniques proposed by different eminent researchers in noise removal, contrast enhancement, thorax removal, lung segmentation, bone suppression, segmentation of trachea, classification of nodule and nonnodule and final classification of benign and malignant nodules.
Results: A comparison of the performance of different techniques implemented by various researchers for the classification of nodule and non-nodule has been tabulated in the paper.
Conclusion: The findings of this review paper will definitely prove to be useful to the research community working on automation of lung nodule detection.
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http://dx.doi.org/10.2174/1573405615666190206153321 | DOI Listing |
PLoS One
January 2025
Faculty of Computer Science and Information Technology, Universiti Malaya, Kuala Lumpur, Malaysia.
Background: Online malicious attempts such as scamming continue to proliferate across the globe, aided by the ubiquitous nature of technology that makes it increasingly easy to dupe individuals. This study aimed to identify the predictors for online fraud victimization focusing on Personal, Environment and Behavior (PEB).
Methods: Social Cognitive Theory (SCT) was used as a guide in developing the PEB framework.
R I Med J (2013)
February 2025
Alpert Medical School of Brown University, Department of Medicine, Division of Cardiology, Rhode Island Hospital.
Cardiac Positron Emission Tomography (PET) is a power- ful imaging tool with diverse applications in the detection and diagnosis of various cardiac conditions, including inflammatory, infectious, and neoplastic processes. Using the radiotracer 18F-fluorodeoxyglucose (18F-FDG), cardiac PET enables the identification of cardiac involvement in diseases such as sarcoidosis and severe infections affecting the heart tissue. Additionally, 18F-FDG PET is valuable in the evaluation of cardiac masses, helping to assess their metabolic activity and potential malignancy.
View Article and Find Full Text PDFPest Manag Sci
January 2025
State Key Laboratory of Elemento-Organic Chemistry, Department of Chemistry, Nankai University, Tianjin, China.
Background: Increasing the diversity of lead compounds has been shown to enhance the efficacy of diamide insecticides. Fifty novel compounds were precisely designed and synthesized utilizing fragment-based assembly and virtual screening coupling.
Results: The median lethal concentration (LC) values of compounds X-30 and X-40 against Mythimna separata were 0.
J Org Chem
January 2025
Institute of Theoretical Chemistry and College of Chemistry, Jilin University, Changchun 130023, P.R. China.
Thiophene and pyrrole units are extensively utilized in light-responsive materials and have significantly advanced the field of organic photovoltaics (OPV). This progress has inspired our exploration of photosensitizers (PS) for photodynamic therapy (PDT). Currently, traditional PS face limitations in clinical application, including a restricted variety and narrow applicability.
View Article and Find Full Text PDFNeurooncol Adv
January 2025
Imaging AI Group, Luxembourg Centre for Systems Biomedicine, University of Luxembourg, Belvaux, Luxembourg.
Background: Publicly available data are essential for the progress of medical image analysis, in particular for crafting machine learning models. Glioma is the most common group of primary brain tumors, and magnetic resonance imaging (MRI) is a widely used modality in their diagnosis and treatment. However, the availability and quality of public datasets for glioma MRI are not well known.
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