Liposomes for Improved Enzymatic Glycosylation of Lipid-Modified Lactose Enkephalin.

Chempluschem

School of Chemistry and Molecular Biosciences, The University of Queensland, Cooper Road, St Lucia, QLD 4072 (Australia), Fax: (+61) 7-33654273.

Published: August 2013

AI Article Synopsis

  • Liposome formulations helped increase the solubility of a lipid-modified lactose enkephalin.
  • When liposomes were used during enzymatic transformation, there was a twofold increase in glycosylation.
  • This improvement was significant compared to using a 5% dimethyl sulfoxide (DMSO) solution for substrate solubilization.

Article Abstract

Liposomes and enzymes: Liposome formulations improved solubility of a lipid-modified lactose enkephalin and, when used in enzymatic transformation, led to a twofold increase in glycosylation in comparison to substrate solubilised in 5 % dimethyl sulfoxide (DMSO; see figure).

Download full-text PDF

Source
http://dx.doi.org/10.1002/cplu.201300115DOI Listing

Publication Analysis

Top Keywords

lipid-modified lactose
8
lactose enkephalin
8
liposomes improved
4
improved enzymatic
4
enzymatic glycosylation
4
glycosylation lipid-modified
4
enkephalin liposomes
4
liposomes enzymes
4
enzymes liposome
4
liposome formulations
4

Similar Publications

Liposomes for Improved Enzymatic Glycosylation of Lipid-Modified Lactose Enkephalin.

Chempluschem

August 2013

School of Chemistry and Molecular Biosciences, The University of Queensland, Cooper Road, St Lucia, QLD 4072 (Australia), Fax: (+61) 7-33654273.

Article Synopsis
  • Liposome formulations helped increase the solubility of a lipid-modified lactose enkephalin.
  • When liposomes were used during enzymatic transformation, there was a twofold increase in glycosylation.
  • This improvement was significant compared to using a 5% dimethyl sulfoxide (DMSO) solution for substrate solubilization.
View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!