Appearing with a trace! A new colorimetric nanosensor for Cr from the amyloid fibrils of hen lysozyme has been developed. This nanosensor, which makes use of hen lysozyme fibrils as Cr binders and acidified diphenylcarbazide (DPC) as the colorimetric probe, can specifically detect Cr at the ppb level without sample pretreatment and the use of advanced instruments.
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http://dx.doi.org/10.1002/cplu.201300267 | DOI Listing |
Talanta
December 2024
Department of Pharmacy, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Ji'nan, Shandong, 250021, PR China. Electronic address:
Methotrexate (MTX) is a widely used antimetabolite drug, mainly used in the treatment of a variety of cancer. Given the low therapeutic index and significant individual variability of MTX, it was critical to perform therapeutic drug monitoring (TDM) to minimize the side effects. Here, we designed a rapid and sensitive fluorescence/colorimetric assay for the detection of MTX in diluted human serum.
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December 2024
Functional Nanomaterials Laboratory, Center for Micro/Nanomaterials and Technology, and Key Laboratory of Photochemical Conversion and Optoelectronic Materials, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing, 100190, China. Electronic address:
The differentiation of valence states plays a crucial role in determining the toxicity of chromium (Cr) in environmental samples. In this work, two modes of colorimetric and electrochemical analytical methods based on a fungus like porous CoS (FP CoS) nanosensor were developed for rapid, specific, and portable detection trace/ultra-trace chromium species (Cr(VI) and Cr(III)). The FP CoS exhibited peroxidase activity as a nanozyme for the colorimetric detection of Cr(VI), catalyzing the oxidation of 3,3',5,5'-tetramethylbenzidine (TMB) to a blue oxidation product (oxTMB) in the presence of Cr(VI) instead of unstable HO as an oxidizer at room temperature over existing methods.
View Article and Find Full Text PDFBiosens Bioelectron
February 2025
Key Laboratory of Photochemical Biomaterials and Energy Storage Materials, Heilongjiang Province, College of Chemistry and Chemical Engineering, Harbin Normal University, Harbin, 150025, PR China. Electronic address:
Glucose detection is critical for diabetes diagnosis and management. This study aimed to develop an enzyme-free, cascade-based, triple-readout paper sensor utilizing bismuth (Bi)-based metal-organic frameworks/gold nanoparticles (Bi-BDC-NH@Au) for detecting urine glucose. Herein, Bi-BDC-NH@Au exhibited glucose oxidase-like activity and oxidized glucose to generate HO, which then quenched the blue fluorescence of FP@Bi-BDC-NH@Au through an inner filter effect.
View Article and Find Full Text PDFSpectrochim Acta A Mol Biomol Spectrosc
February 2025
School of Chemical Sciences, Universiti Sains Malaysia, 11800 Pulau Pinang, Malaysia.
In this study, mannitol-functionalized magnetic nanoparticles (MMNPs) as a unique nanosorbent and N-doped fluorescent carbon dots (N-CDs) as a cost-effective nanosensor were created and utilized, for the first time, for dispersive micro-solid-phase extraction (Dµ-SPE) to determine carmine (E120) dye in water samples and juices. The modification of the magnetic nanoparticles with mannitol was designed to enhance the responsive potential for adsorption of the polar E120 dye from complex sample matrices through electrostatic interaction. The as-fabricated N-CDs fluorescent probe exhibited a high fluorescence quantum yield (Φs) of 43.
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February 2025
Biological Nanotechnology Research Institute, Ludong University, Yantai, Shandong, 264025, China; School of Life Sciences, Ludong University, Yantai, Shandong, 264025, China; School of Food Engineering, Ludong University, Yantai, Shandong, 264025, China. Electronic address:
Timely and accurate on-site detection of ochratoxin A (OTA) is extremely important for global public health. In this study, a fluorescence/colorimetric biosensor based on TiC nano-materials (TiC-NMS) and a machine-learning (ML) based fluorescence/colorimetric intelligent learning system for detection of OTA concentration (COTA) were developed. The sensor was fabricated by functionalizing TiC-NMS prepared by physical-exfoliation assisted metal-ion-induction using ssDNA.
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