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How I do it: Modified operation technique for MR Conditional OSIA 3: anterior based flap for covering the implant.
Eur Arch Otorhinolaryngol
January 2025
Department of Otorhinolaryngology, Head and Neck Surgery, Ruhr Universitiy Bochum, St. Elisabeth-Hospital, Bochum, Germany.
Background: The new OSIA3 is 1.5 T and 3 T MR-Conditional. Skin related issues are the most common complications.
View Article and Find Full Text PDFT-Shaped Wedge Resection of the Upper Eyelid: An Alternative to the Pentagonal Wedge.
Ophthalmic Plast Reconstr Surg
January 2025
Department of Ophthalmology, Columbia University Medical Center, New York, New York.
Purpose: To report the experience with an alternative to the upper eyelid pentagonal wedge resection technique which results in improved cosmesis due to a greater alignment of incisions with relaxed skin tension lines.
Methods: A retrospective review of all patients who underwent the T-shaped wedge resection by the authors from 2009 to 2017. A horizontal eyelid crease incision is made across the upper eyelid skin.
Correlation analysis of DLG5 and PD-L1 expression in triple-negative breast cancer.
BMC Cancer
January 2025
Shaanxi Engineering Research Center of Cell Immunology, Shaanxi Provincial People's Hospital, Xi'an, Shaanxi, China.
Background: Triple-negative breast cancer (TNBC) is among the most aggressive forms of breast cancer, characterized by a dismal prognosis. In the absence of drug-targetable receptors, chemotherapy remains the sole systemic treatment alternative. Recent advancements in immunotherapy, particularly immune checkpoint inhibitors (ICIs) that target programmed death 1/programmed death ligand 1 (PD-1/PD-L1) and cytotoxic T lymphocyte associated antigen 4 (CTLA-4), have provided renewed optimism for the treatment of patients with TNBC.
View Article and Find Full Text PDFTrimethoprim-Sulfamethoxazole-Induced Pancytopenia: A Case Report.
Cureus
December 2024
Department of Internal Medicine, LewisGale Medical Center, Roanoke, USA.
Pancytopenia is defined as a decrease in all three myeloid cell lines, usually from a precipitating factor such as an autoimmune condition, prescription drug, or several other factors. The etiology of pancytopenia can be determined through laboratory testing, a peripheral blood smear, and a thorough history and physical examination. Trimethoprim-sulfamethoxazole (TMP/SMX, also known by the brand name of Bactrim® or Septra®) is known to cause pancytopenia in rare cases.
View Article and Find Full Text PDFS100A8 promotes tumor progression by inducing phenotypic polarization of microglia through the TLR4/IL-10 signaling pathway in glioma.
J Natl Cancer Cent
December 2024
Department of Neurosurgery, Fudan University Shanghai Cancer Center, Shanghai, China.
Background: S100A8 is a member of the S100 protein family and plays a pivotal role in regulating inflammation and tumor progression. This study aimed to comprehensively assess the expression patterns and functional roles of S100A8 in glioma progression.
Methods: Glioma tissues were collected from 98 patients who underwent surgical treatment at Fudan University Shanghai Cancer Center.
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