Introduction: Transcarpathian region refers to the climate-geographic zone with a low level of fluoride and iodine in the environment and as shown by the epidemiological survey «very high» according to WHO criteria for the level of intensity of main dental diseases. With the purpose of directing the implementation of the state policy in the field of health care and for the prevention of dental diseases, the industrial release of a functional food product - «DentesVita» enriched with iodine and fluorine - has been adjusted. The aim: Was to study the effectiveness of the use of functional food product - DentesVita for the prevention of dental caries in children.

Material And Methods: A comprehensive dental examination of 180 children of 12 years of age has been carried out: 60 of them in each of the climatic and geographical zones of Transcarpathia: plain, foothills and mountains. The intensity of caries according to the DMF index, increase of intensity was determined. A simplified hygiene index (OHI-S) was used to assess the hygienic state of the oral cavity. Carried out research on the mineralization potential of saliva.

Results: The growth of caries in children of the main group of the plain zone was 1.8 times smaller, and in the foothills and mountains 1.6 times smaller than the similar rates of control group children (p <0.05). The caries prophylactic effect at that was among schoolchildren in the plain zone: 43.48%, foothill - 38.66%, and mountainous - 23.53%.

Conclusions: These studies confirm the effectiveness of using «DentesVita» for the prevention of dental caries in children living in conditions of biogeochemical deficiency of fluorine and iodine on the basis of caries intensity growth indexes, hygienic indexes of the oral cavity and mineralizing ability of oral liquid.

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