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[Clinical variables and management of disseminated granuloma annulare - monocentric retrospective analysis of 33 cases between 2021 and 2023].
Dermatologie (Heidelb)
January 2025
Klinik und Poliklinik für Dermatologie und Allergologie, Universitätsklinikum Regensburg, Franz-Josef-Strauß-Allee 11, 93053, Regensburg, Deutschland.
Article Synopsis
- Granuloma annulare (GA) is a non-infectious skin condition that can become widespread in some patients; this study focused on those with disseminated GA in a German hospital.
- A total of 239 patients were studied, with 33 having confirmed disseminated GA, predominantly affecting women around the age of 57, and many reporting little to no symptoms.
- Treatment options included glucocorticoids and phototherapy, but only a small percentage achieved remission, highlighting the need for more effective clinical trials for new therapies.
Remission of necrobiotic xanthogranuloma after intravenous immunoglobulin interruption: A case report.
SAGE Open Med Case Rep
August 2024
Department of Dermatology, Hôtel-Dieu de Lévis, Lévis, Québec, QC, Canada.
Necrobiotic xanthogranuloma is a rare non-Langerhans cell histiocytosis with the potential for multisystemic involvement. It's a challenging disease to treat and multiple treatments have been reported in the literature with variable results. We present the case of a 92-year-old woman with multiple orange-brown papules and plaques on her face progressing for several years.
View Article and Find Full Text PDFThe realistic positioning of UVA1 phototherapy after 25 years of clinical experience and the availability of new biologics and small molecules: a retrospective clinical study.
Front Med (Lausanne)
November 2023
Department of Dermatology, University of Brescia, Brescia, Italy.
Article Synopsis
- Ultraviolet (UVA) A1 phototherapy has been an effective treatment for various skin conditions since the 1990s, yet its application remains limited to a few dermatology centers even after 30 years.
- A study at a single center reviewed 740 patients treated from 1998 to 2022, assessing treatment outcomes and side effects, revealing significant improvements in several conditions, including morphea and skin sarcoidosis.
- Despite showing good efficacy, the usage of UVA1 phototherapy has decreased over the years due to multiple factors, including possible changes in clinical practices and alternatives available.
Clinical Manifestations and Management of Pediatric Granuloma Annulare: A Systematic Review.
J Pediatr
June 2023
Department of Dermatology and Reference Center for Rare Diseases and Vascular Malformations (MAGEC), CHRU Tours, Tours, France; Unit of Pediatric Dermatology, CHRU Tours, Tours, France; Universities of Tours and Nantes, INSERM 1246-SPHERE, Tours, France.
Objective: To determine the clinical manifestations, management, and outcomes of pediatric granuloma annulare (GA).
Study Design: We searched MEDLINE via PubMed, Latin American and Caribbean Health Sciences, and EMBASE from inception to January 2021. We included all original reports of patients <18 years of age with a diagnosis of GA and all original reports describing any intervention, including topical or systemic agents, in these patients.
Background: Lenalidomid ranks among immunomodulatory drugs. There are a few of the more common side effects, like a higher risk of venous trombembolism or diarrhea. Other side effects are rare.
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