Changes in left ventricular blood flow during diastole due to differences in chamber size in healthy dogs.

Sci Rep

Department of Veterinary Surgery, Tokyo University of Agriculture and Technology, Animal Medical Center, 3-5-8 Saiwaicho, 183-8509, Fuchu-shi, Tokyo, Japan.

Published: January 2020

AI Article Synopsis

  • Vorticity is a new measure that helps assess how well the left ventricle of the heart functions during the diastolic phase, which is when the heart fills with blood.
  • The size of the ventricle can greatly affect how blood flows during this filling phase, and the study evaluated this impact using a variety of dog breeds with different body sizes.
  • Results showed that vorticity decreases as the ventricular chamber length increases, indicating that size plays a crucial role in diastolic function, highlighting the importance of considering ventricular size in both veterinary medicine and pediatric cardiology.

Article Abstract

Vorticity is a novel index that reflects diastolic function of left ventricle. The size of the ventricle can influence the ventricular diastolic blood flow. We evaluated effect of ventricular size on diastolic function and diastolic intracardiac blood flow using a particular species of dogs, which has a wide range of body size. Vector flow mapping was used for evaluation of intracardiac blood flow, and intraventricular pressure gradient (IVPG) was used for evaluation of diastolic function. 58 dogs weighing 1.3-42.3 kg were included in this study. Vorticity was found to be inversely proportional to the length of the ventricular chamber. Intraventricular pressure difference was positively correlated with the length of the left ventricle, whereas IVPG was not. This study showed that the vorticity is influenced by the size of the left ventricle independently of other factors. To evaluate the hemodynamic state of each individual appropriately by using vorticity and IVPD, ventricular size should be taken into account especially in the field of veterinary medicine and human pediatric and adolescent cardiology.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6981119PMC
http://dx.doi.org/10.1038/s41598-019-57180-6DOI Listing

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