AI Article Synopsis

  • CKD patients are at high risk for early death due to cardiovascular events, often developing abnormalities before reaching end-stage renal disease (ESRD).
  • A study involving 100 CKD patients used ECG and Echo to assess asymptomatic cardiovascular issues, revealing that 72% had ECG abnormalities and 56% had Echo abnormalities.
  • Key findings included a high prevalence of left ventricular hypertrophy (LVH) and a greater likelihood of LVH detection in women, with significant abnormalities noted particularly in patients on dialysis.

Article Abstract

Introduction: Chronic Kidney Disease patients face extraordinary risk for premature death, because of cardiovascular events. This increased risk of CV events may begin during early stages of CKD much before the onset of ESRD. Our study aim was to non-invasively identify prevalence of various asymptomatic cardiovascular abnormalities using ECG & Echo changes in patients with CKD.

Material: sample of 100 patients enrolled, 2D Echo & ECG was used after ethical approval and consent

Observations: mean age of patients 48.99±SD15.8 years. 82% presented within 6-months of diagnosis. Male:Female ratio = 2:1. Hypertension (44%) was the leading etiology, cardiovascular abnormalities detected in 72% by ECG & 56% by Echo. LVH was the commonest abnormality (14 by ECG, 34 by Echo, 9 by both). Females were 1.7 times more likely to be detected LVH by Echo than males. LVH was 2 times more in on-dialysis patients. Hyperkalemia & Pericardial Effusion in ECG were more evident in on-dialysis patients. Conduction abnormality were more common in patients on dialysis. Echo revealed LV diastolic dysfunction in 46, LV systolic dysfunction in 16, pericardial effusion in 19 patients

Conclusions: Asymptomatic cardiovascular abnormalities in such significant percentage of patients should enlighten the clinicians regarding CVD in CKD.

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