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| http://dx.doi.org/10.1007/s40614-018-0163-8 | DOI Listing |
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Nicotine enhances the stemness and tumorigenicity in intestinal stem cells via Hippo-YAP/TAZ and Notch signal pathway.
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Department of Diabetes and Metabolic Diseases, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Cigarette smoking is a well-known risk factor inducing the development and progression of various diseases. Nicotine (NIC) is the major constituent of cigarette smoke. However, knowledge of the mechanism underlying the NIC-regulated stem cell functions is limited.
View Article and Find Full Text PDFSymbolic dynamics of joint brain states during dyadic coordination.
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Department of Cognitive Sciences, University of California, Irvine, California 92617, USA.
We propose a novel approach to investigate the brain mechanisms that support coordination of behavior between individuals. Brain states in single individuals defined by the patterns of functional connectivity between brain regions are used to create joint symbolic representations of brain states in two or more individuals to investigate symbolic dynamics that are related to interactive behaviors. We apply this approach to electroencephalographic data from pairs of subjects engaged in two different modes of finger-tapping coordination tasks (synchronization and syncopation) under different interaction conditions (uncoupled, leader-follower, and mutual) to explore the neural mechanisms of multi-person motor coordination.
View Article and Find Full Text PDFNovel patterns in discrete Ikeda map: Quint points and complex non-quantum chirality.
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School of Mechanical and Power Engineering, Zhengzhou University, Science Road 100, 450001 Zhengzhou, China.
In this paper, the complex and dynamically rich distribution of stable phases in the well-known discrete Ikeda map is studied in detail. The unfolding patterns of these stable phases are described through three complementary stability diagrams: the Lyapunov stability diagram, the isoperiod stability diagram, and the isospike stability diagram. The adding-doubling complexification cascade and fascinating non-quantum chiral pairs are discovered, marking the first report of such structures in discrete mapping.
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Centre for Mathematical Science, Lund University, Märkesbacken 4, 223 62 Lund, Sweden.
We investigate the dynamics of the adaptive Kuramoto model with slow adaptation in the continuum limit, N→∞. This model is distinguished by dense multistability, where multiple states coexist for the same system parameters. The underlying cause of this multistability is that some oscillators can lock at different phases or switch between locking and drifting depending on their initial conditions.
View Article and Find Full Text PDFThe evolution of cooperation in spatial public goods game with tolerant punishment based on reputation threshold.
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Department of Computer Science and A.I. Andalusian Research Institute DaSCI "Data Science and Computational Intelligence, " University of Granada, 18071 Granada, Spain.
Reputation and punishment are significant guidelines for regulating individual behavior in human society, and those with a good reputation are more likely to be imitated by others. In addition, society imposes varying degrees of punishment for behaviors that harm the interests of groups with different reputations. However, conventional pairwise interaction rules and the punishment mechanism overlook this aspect.
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