Background: Motor response suppression can be regarded as an important aspect of the executive control, as a way of changing the behavioral pattern depending on the internal state or external factors.
Purpose: The aim of our study was to examine whether there were differences in the ability of cortical inhibition of triggered motor program (in the context of the Stop-Signal task) between females and males.
Methods: We examined differences in the patterns of event-related EEG synchronization/desynchronization (ERS/ERD) in young volunteers under the conditions of complete inhibition of the triggered motor program of a manual movement. Thirty-six male and thirty-eight female (ages of 19 to 21) took part in the tests. The ERS and ERD indices were estimated within the EEG frequency range 8-35 Hz in frontal, central and parietal leads.
Results: In both gender groups, as a global pattern, the prevalence of connected phenomena with the EEG synchronization event in the range of α-activity of the EEG, apparently associated with inhibition of the running motor program was noted.
Conclusion: Cortical electrical activity acquired certain specific features of the frequency-spatial organization, which could indicate the course of somewhat different brain processes of men and women.
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http://dx.doi.org/10.5214/ans.0972.7531.260103 | DOI Listing |
Alzheimers Dement
December 2024
iCBR - Coimbra Institute for Clinical and Biomedical Research, Faculty of Medicine, University of Coimbra, Coimbra, Coimbra, Portugal; Institute of Pharmacology and Experimental Therapeutics, Faculty of Medicine, University of Coimbra, Coimbra, Coimbra, Portugal; CIBB - Center for Innovative Biomedicine and Biotechnology, University of Coimbra, Coimbra, Coimbra, Portugal; Institute of Interdisciplinary Research (IIIUC), University of Coimbra, Coimbra, Coimbra, Portugal; CNC-UC - Center for Neuroscience and Cell Biology, University of Coimbra, Coimbra, Coimbra, Portugal.
Background: Cardiometabolic diseases, such as type 2 diabetes, hypertension, dyslipidemia or obesity, constitute major causes of mortality and morbidity worldwide, especially among middle-aged individuals. The increasing incidence and association with aging and lifestyle, render the cardiometabolic diseases a societal concern. This is further reinforced by their association with an increased risk of cognitive impairment and neurodegenerative diseases (namely dementia and Alzheimer's disease (AD)).
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, Chandigarh, India.
Background: Dementia is a progressive clinical syndrome which is marked by pervasive cognitive impairment and deterioration. With the ever-increasing number of people living with dementia, it has become a global concern. Current medications focus on slowing the progression of dementia and managing the comorbidities and not on directly enhancing memory.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Newcastle University, Newcastle upon Tyne, United Kingdom.
Lewy body dementia (LBD) clinically is characerized by a complex myriad of cognitive, behavioral, motor, sleep and autonomic symptoms that can be challenging to manage, particularly in the context of the fluctuations that are so characteristic for these patients. The DIAMOND Lewy Toolkits offer a resource to support clinicians in recognizing and managing this range of symptoms observed in LBD. This session will provide a guided introduction to the DIAMOND Lewy Toolkits, offering a framework to leverage the toolkits in support of patient centered care.
View Article and Find Full Text PDFAging Cell
January 2025
Department of Neurology, Songjiang Research Institute, Shanghai Key Laboratory of Emotions and Affective Disorders, Songjiang Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Integrating dietary interventions have been extensively studied for their health benefits, such as Alzheimer's disease, Huntington's disease, and aging. However, it is necessary to fully understand the mechanisms of long-term effects and practical applications of these dietary interventions for health. A 10-week intermittent fasting (IMF) regimen was implemented on the aging animals in the current study.
View Article and Find Full Text PDFEur J Neurosci
January 2025
Laboratory of Human Cell Neurophysiology, N.N. Semenov Federal Research Center for Chemical Physics Russian Academy of Sciences, Moscow, Russia.
Excessive beta oscillations in the subthalamic nucleus are established as a primary electrophysiological biomarker for motor impairment in Parkinson's disease and are currently used as feedback signals in adaptive deep brain stimulation systems. However, there is still a need for optimization of stimulation parameters and the identification of optimal biomarkers that can accommodate varying patient conditions, such as ON and OFF levodopa medication. The precise boundaries of 'pathological' oscillatory ranges, associated with different aspects of motor impairment, are still not fully clarified.
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