Healthcare-facility-onset C.difficile LabID events are defined as positive stool samples collected >3 days after hospitalization. Using a definition of >72 hours, we found that 84 of 1013 cases (8.3%) identified as C. difficile LabID events were collected between 48 and 72 hours after admission.
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| http://dx.doi.org/10.1017/ice.2020.3 | DOI Listing |
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Discontinuation of Contact Precautions for Methicillin-resistant Staphylococcus aureus in a Pediatric Healthcare System.
J Pediatric Infect Dis Soc
February 2024
Division of Infectious Disease, Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Background: Many hospitals caring for adult patients have discontinued the requirement for contact precautions (CP) for patients with methicillin-resistant Staphylococcus aureus (MRSA) infection or colonization without reported negative effects. It is not clear whether this experience can be extrapolated to pediatric facilities.
Methods: CP for MRSA were discontinued in all locations except the neonatal intensive care unit at a 3-hospital pediatric healthcare system in September 2019.
Surveillance and epidemiology of Clostridioides difficile infection using the national health surveillance network criteria: A 7-year study from Mumbai, India.
Indian J Med Microbiol
November 2023
Department of Pathology and Microbiology, Breach Candy Hospital Trust, Second Floor, Annex wing, 60 A, Bhulabhai Desai Marg, Breach Candy, Cumballa Hill, Mumbai, Maharashtra, 400026, India. Electronic address:
Introduction: Clostridioides difficile (CD) is a significant cause of morbidity and mortality. While considerable data is available in the developed world regarding Clostridioides difficile infection (CDI), Indian data is sparse especially using the standardized surveillance systems.
Aim And Objectives Of The Study: To identify the incidence, risk factors, and mortality rate associated with CDI in a tertiary care hospital based on the Laboratory-Identified (LabID) event criteria of the Centers for Disease Control and Prevention (CDC) National Health Surveillance Network (NHSN).
Association between prevalence of laboratory-identified infection (CDI) and antibiotic treatment for CDI in US acute-care hospitals, 2019.
Infect Control Hosp Epidemiol
December 2022
Division of Healthcare Quality Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia.
Objective: To evaluate hospital-level variation in using first-line antibiotics for infection (CDI) based on the burden of laboratory-identified (LabID) CDI.
Methods: Using data on hospital-level LabID CDI events and antimicrobial use (AU) for CDI (oral/rectal vancomycin or fidaxomicin) submitted to the National Healthcare Safety Network in 2019, we assessed the association between hospital-level CDI prevalence (per 100 patient admissions) and rate of CDI AU (days of therapy per 1,000 days present) to generate a predicted value of AU based on CDI prevalence and CDI test type using negative binomial regression. The ratio of the observed to predicted AU was then used to identify hospitals with extreme discordance between CDI prevalence and CDI AU, defined as hospitals with a ratio outside of the intervigintile range.
Discontinuing MRSA and VRE contact precautions: Defining hospital characteristics and infection prevention practices predicting safe de-escalation.
Infect Control Hosp Epidemiol
November 2022
Department of Infection Prevention and Control, UPMC Presbyterian, Pittsburgh, Pennsylvania.
Objective: To define conditions in which contact precautions can be safely discontinued for methicillin-resistant (MRSA) and vancomycin-resistant (VRE).
Design: Interrupted time series.
Setting: 15 acute-care hospitals.
Long-term impact of contact precautions cessation for Methicillin-Resistant Staphylococcus Aureus (MRSA).
Am J Infect Control
March 2022
Infection Prevention and Health System Epidemiology, Atrium Health Wake Forest Baptist, Winston-Salem, NC. Electronic address:
Article Synopsis
- Methicillin-Resistant Staphylococcus aureus (MRSA) is a significant cause of healthcare-associated infections, leading to traditional contact isolation practices that are now being reevaluated.
- A study at a university hospital over 68 months examined MRSA infection rates before and after stopping contact isolation, analyzing various infection types using statistical methods.
- Results showed no significant increase in MRSA infection rates post-isolation discontinuation, while annual savings from reduced isolation costs amounted to $139,228.
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